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GO Annotations Graph
Symbol
Name
ID
Itga5
integrin alpha 5 (fibronectin receptor alpha)
MGI:96604

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0050839cell adhesion molecule bindingISOJ:155856
Molecular FunctionGO:0005154epidermal growth factor receptor bindingISOJ:155856
Molecular FunctionGO:0005178integrin bindingIPIJ:31981
Molecular FunctionGO:0005178integrin bindingISOJ:155856
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0005515protein bindingIPIJ:84858
Molecular FunctionGO:0005515protein bindingIPIJ:222137
Molecular FunctionGO:0005515protein bindingIPIJ:84472
Cellular ComponentGO:0009986cell surfaceIDAJ:16243
Cellular ComponentGO:0009986cell surfaceIDAJ:193934
Cellular ComponentGO:0009986cell surfaceISOJ:164563
Cellular ComponentGO:0005911colocalizes_with
cell-cell junction
ISOJ:164563
Cellular ComponentGO:0005737cytoplasmISOJ:155856
Cellular ComponentGO:0031410cytoplasmic vesicleIDAJ:215661
Cellular ComponentGO:0005783endoplasmic reticulumIDAJ:215661
Cellular ComponentGO:0009897external side of plasma membraneIDAJ:47279
Cellular ComponentGO:0009897external side of plasma membraneIDAJ:125138
Cellular ComponentGO:0005925focal adhesionISOJ:164563
Cellular ComponentGO:0005925colocalizes_with
focal adhesion
ISOJ:164563
Cellular ComponentGO:0005794Golgi apparatusIDAJ:215661
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0008305integrin complexISOJ:155856
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0005886plasma membraneIDAJ:215661
Cellular ComponentGO:0032587colocalizes_with
ruffle membrane
ISOJ:164563
Cellular ComponentGO:0045202synapseIDAJ:84858
Biological ProcessGO:0007155cell adhesionISOJ:155856
Biological ProcessGO:0033631cell-cell adhesion mediated by integrinIMPJ:125138
Biological ProcessGO:0031589cell-substrate adhesionISOJ:164563
Biological ProcessGO:0007044cell-substrate junction assemblyIDAJ:84472
Biological ProcessGO:0035987endodermal cell differentiationISOJ:164563
Biological ProcessGO:0007157heterophilic cell-cell adhesion via plasma membrane cell adhesion moleculesIMPJ:125138
Biological ProcessGO:0034113heterotypic cell-cell adhesionISOJ:164563
Biological ProcessGO:0007229integrin-mediated signaling pathwayISOJ:155856
Biological ProcessGO:0007159leukocyte cell-cell adhesionIMPJ:125138
Biological ProcessGO:0007613memoryIMPJ:84858
Biological ProcessGO:2000811negative regulation of anoikisISOJ:164563
Biological ProcessGO:0030335positive regulation of cell migrationISOJ:155856
Biological ProcessGO:0010811positive regulation of cell-substrate adhesionISOJ:155856
Biological ProcessGO:0050731positive regulation of peptidyl-tyrosine phosphorylationISOJ:164563
Biological ProcessGO:1903672positive regulation of sprouting angiogenesisISOJ:164563
Biological ProcessGO:0045765regulation of angiogenesisIGIJ:149995


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/05/2021
MGI 6.16
The Jackson Laboratory