GO Annotations Graph

• Symbol: Il1r2
• Name: interleukin 1 receptor, type II
• ID: MGI:96546

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019966	interleukin-1 binding	IBA	J:265628
Molecular Function	GO:0019966	interleukin-1 binding	IPI	J:193599
Molecular Function	GO:0004908	interleukin-1 receptor activity	IBA	J:265628
Molecular Function	GO:0004908	interleukin-1 receptor activity	IPI	J:193599
Molecular Function	GO:0004910	interleukin-1, type II, blocking receptor activity	IEA	J:72247
Cellular Component	GO:0005737	cytoplasm	IDA	J:193599
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Biological Process	GO:1900016	negative regulation of cytokine production involved in inflammatory response	IMP	J:193599
Biological Process	GO:0032690	negative regulation of interleukin-1 alpha production	IMP	J:193599
Biological Process	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway	IPI	J:193599
Biological Process	GO:0010955	negative regulation of protein processing	IMP	J:193599
Biological Process	GO:0016485	protein processing	IMP	J:193599