Hras GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Hras
Harvey rat sarcoma virus oncogene
MGI:96224

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003925	G protein activity	IEA	J:72245
Molecular Function	GO:0019003	GDP binding	ISO	J:164563
Molecular Function	GO:0019003	GDP binding	IBA	J:265628
Molecular Function	GO:0005525	GTP binding	ISO	J:164563
Molecular Function	GO:0005525	GTP binding	IBA	J:265628
Molecular Function	GO:0005525	GTP binding	IDA	J:145651
Molecular Function	GO:0003924	GTPase activity	ISO	J:164563
Molecular Function	GO:0003924	GTPase activity	IBA	J:265628
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:46202
Molecular Function	GO:0005515	protein binding	IPI	J:194542
Molecular Function	GO:0005515	protein binding	IPI	J:64313
Molecular Function	GO:0005515	protein binding	IPI	J:137819
Molecular Function	GO:0005515	protein binding	IPI	J:91790
Molecular Function	GO:0005515	protein binding	IPI	J:36812
Molecular Function	GO:0005515	protein binding	IPI	J:117391
Molecular Function	GO:0005515	protein binding	IPI	J:145651
Molecular Function	GO:0043539	protein serine/threonine kinase activator activity	IDA	J:104992
Molecular Function	GO:0043539	protein serine/threonine kinase activator activity	IDA	J:104992
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0043495	protein-membrane adaptor activity	IDA	J:104992
Molecular Function	GO:0043495	protein-membrane adaptor activity	IDA	J:104992
Molecular Function	GO:0043495	protein-membrane adaptor activity	IDA	J:104992
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:1905360	GTPase complex	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9029152
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-NUL-1250468
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-NUL-1250472
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:124964
Biological Process	GO:0060612	adipose tissue development	IMP	J:298397
Biological Process	GO:0006915	apoptotic process	ISO	J:155856
Biological Process	GO:0071480	cellular response to gamma radiation	ISO	J:164563
Biological Process	GO:0090398	cellular senescence	ISO	J:164563
Biological Process	GO:0090398	cellular senescence	IBA	J:265628
Biological Process	GO:0090398	cellular senescence	IDA	J:95113
Biological Process	GO:0090398	cellular senescence	IDA	J:84791
Biological Process	GO:0042832	defense response to protozoan	IMP	J:173261
Biological Process	GO:0006897	endocytosis	IDA	J:81687
Biological Process	GO:0048144	fibroblast proliferation	IDA	J:106576
Biological Process	GO:0008286	insulin receptor signaling pathway	IDA	J:326913
Biological Process	GO:0008286	insulin receptor signaling pathway	IDA	J:326913
Biological Process	GO:0048009	insulin-like growth factor receptor signaling pathway	ISO	J:327224
Biological Process	GO:0097193	intrinsic apoptotic signaling pathway	IMP	J:117391
Biological Process	GO:0097193	intrinsic apoptotic signaling pathway	IGI	J:117391
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:164563
Biological Process	GO:0034260	negative regulation of GTPase activity	ISO	J:164563
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IDA	J:63722
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IGI	J:63722
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IGI	J:63722
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IGI	J:63722
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IGI	J:63722
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IGI	J:63722
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IGI	J:63722
Biological Process	GO:0051402	neuron apoptotic process	IGI	J:63722
Biological Process	GO:0051402	neuron apoptotic process	IGI	J:63722
Biological Process	GO:0051402	neuron apoptotic process	IDA	J:63722
Biological Process	GO:0090402	oncogene-induced cell senescence	IDA	J:72780
Biological Process	GO:2000251	positive regulation of actin cytoskeleton reorganization	ISO	J:164563
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	IPI	J:88364
Biological Process	GO:0045740	positive regulation of DNA replication	ISO	J:155856
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	ISO	J:164563
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ISO	J:155856
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ISO	J:164563
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	IDA	J:106576
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:170688
Biological Process	GO:0043547	positive regulation of GTPase activity	ISO	J:164563
Biological Process	GO:0046330	positive regulation of JNK cascade	ISO	J:164563
Biological Process	GO:0043406	positive regulation of MAP kinase activity	ISO	J:164563
Biological Process	GO:0043410	positive regulation of MAPK cascade	ISO	J:164563
Biological Process	GO:2000630	positive regulation of miRNA metabolic process	ISO	J:164563
Biological Process	GO:0010863	positive regulation of phospholipase C activity	ISO	J:164563
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:0090314	positive regulation of protein targeting to membrane	ISO	J:164563
Biological Process	GO:0046579	positive regulation of Ras protein signal transduction	ISO	J:145554
Biological Process	GO:1900029	positive regulation of ruffle assembly	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0032729	positive regulation of type II interferon production	IMP	J:173261
Biological Process	GO:0090303	positive regulation of wound healing	ISO	J:164563
Biological Process	GO:0007265	Ras protein signal transduction	IGI	J:76551
Biological Process	GO:0007265	Ras protein signal transduction	ISO	J:164563
Biological Process	GO:0007265	Ras protein signal transduction	ISO	J:155856
Biological Process	GO:0007265	Ras protein signal transduction	IBA	J:265628
Biological Process	GO:0007265	Ras protein signal transduction	TAS	J:62962
Biological Process	GO:0051726	regulation of cell cycle	ISO	J:164563
Biological Process	GO:0042127	regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0048169	regulation of long-term neuronal synaptic plasticity	IMP	J:98903
Biological Process	GO:0043405	regulation of MAP kinase activity	ISO	J:164563
Biological Process	GO:0098696	regulation of neurotransmitter receptor localization to postsynaptic specialization membrane	ISO	J:164563
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0007165	signal transduction	IEA	J:72247
Biological Process	GO:0007264	small GTPase mediated signal transduction	IDA	J:88364
Biological Process	GO:0050852	T cell receptor signaling pathway	IMP	J:173261
Biological Process	GO:0042088	T-helper 1 type immune response	IMP	J:173261

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23