Hesx1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Hesx1
homeobox gene expressed in ES cells
MGI:96071

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:114817
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IEA	J:72247
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	J:239206
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:297346
Molecular Function	GO:0005515	protein binding	IPI	J:133257
Molecular Function	GO:0005515	protein binding	IPI	J:133257
Molecular Function	GO:0005515	protein binding	IPI	J:133257
Molecular Function	GO:0005515	protein binding	IPI	J:133257
Molecular Function	GO:0005515	protein binding	IPI	J:133257
Molecular Function	GO:0005515	protein binding	IPI	J:133257
Molecular Function	GO:0005515	protein binding	IPI	J:133257
Molecular Function	GO:0005515	protein binding	IPI	J:133257
Molecular Function	GO:0005515	protein binding	IPI	J:133257
Molecular Function	GO:0042803	protein homodimerization activity	IDA	J:297466
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:239206
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:239206
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:297466
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:297346
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	IMP	J:297465
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:133257
Biological Process	GO:0007420	brain development	IMP	J:74125
Biological Process	GO:0043010	camera-type eye development	IMP	J:142649
Biological Process	GO:0060070	canonical Wnt signaling pathway	IMP	J:135132
Biological Process	GO:0071276	cellular response to cadmium ion	IDA	J:297615
Biological Process	GO:0070371	ERK1 and ERK2 cascade	IMP	J:294762
Biological Process	GO:0030900	forebrain development	IMP	J:135132
Biological Process	GO:0030900	forebrain development	IDA	J:229338
Biological Process	GO:0030900	forebrain development	IMP	J:47920
Biological Process	GO:0048853	forebrain morphogenesis	IMP	J:63681
Biological Process	GO:0048853	forebrain morphogenesis	IMP	J:47920
Biological Process	GO:0010467	gene expression	IDA	J:297466
Biological Process	GO:0010467	gene expression	IDA	J:297356
Biological Process	GO:0010467	gene expression	IDA	J:239206
Biological Process	GO:0008406	gonad development	IGI	J:142425
Biological Process	GO:0048861	leukemia inhibitory factor signaling pathway	IMP	J:294762
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0035264	multicellular organism growth	IGI	J:142425
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:133257
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:239206
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0043584	nose development	IMP	J:47920
Biological Process	GO:0043584	nose development	IMP	J:47920
Biological Process	GO:0030916	otic vesicle formation	IMP	J:47920
Biological Process	GO:0021983	pituitary gland development	ISO	J:164563
Biological Process	GO:0021983	pituitary gland development	IBA	J:265628
Biological Process	GO:0021983	pituitary gland development	IMP	J:73085
Biological Process	GO:0021983	pituitary gland development	IGI	J:142425
Biological Process	GO:0021983	pituitary gland development	IMP	J:142649
Biological Process	GO:0021983	pituitary gland development	IMP	J:142649
Biological Process	GO:0021983	pituitary gland development	IMP	J:47920
Biological Process	GO:0021983	pituitary gland development	IMP	J:158763
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0045995	regulation of embryonic development	IMP	J:294762
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0048863	stem cell differentiation	IMP	J:294762
Biological Process	GO:0019827	stem cell population maintenance	IMP	J:297356
Biological Process	GO:0030878	thyroid gland development	IGI	J:142425
Biological Process	GO:0016055	Wnt signaling pathway	IDA	J:229338

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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