GO Annotations Graph

• Symbol: Gria2
• Name: glutamate receptor, ionotropic, AMPA2 (alpha 2)
• ID: MGI:95809

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004971	AMPA glutamate receptor activity	ISO	J:155856
Molecular Function	GO:0004971	AMPA glutamate receptor activity	IBA	J:265628
Molecular Function	GO:0001540	amyloid-beta binding	ISO	J:155856
Molecular Function	GO:0051117	ATPase binding	ISO	J:155856
Molecular Function	GO:0008092	cytoskeletal protein binding	ISO	J:155856
Molecular Function	GO:0005234	extracellularly glutamate-gated ion channel activity	IDA	J:87180
Molecular Function	GO:0035254	glutamate receptor binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0019865	immunoglobulin binding	ISO	J:155856
Molecular Function	GO:0004970	ionotropic glutamate receptor activity	ISO	J:155856
Molecular Function	GO:0004970	ionotropic glutamate receptor activity	ISO	J:164563
Molecular Function	GO:0004970	ionotropic glutamate receptor activity	IDA	J:87180
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	ISO	J:155856
Molecular Function	GO:0015277	kainate selective glutamate receptor activity	ISO	J:155856
Molecular Function	GO:0015276	ligand-gated monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	ISO	J:155856
Molecular Function	GO:0005216	monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0030165	PDZ domain binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:175149
Molecular Function	GO:0005515	protein binding	IPI	J:81682
Molecular Function	GO:0005515	protein binding	IPI	J:177195
Molecular Function	GO:0005515	protein binding	IPI	J:173768
Molecular Function	GO:0005515	protein binding	IPI	J:322380
Molecular Function	GO:0005515	protein binding	IPI	J:200294
Molecular Function	GO:0005515	protein binding	IPI	J:135974
Molecular Function	GO:0005515	protein binding	IPI	J:158601
Molecular Function	GO:0005515	protein binding	IPI	J:173768
Molecular Function	GO:0005515	protein binding	IPI	J:243400
Molecular Function	GO:0005515	protein binding	IPI	J:294276
Molecular Function	GO:0005515	protein binding	IPI	J:100200
Molecular Function	GO:0005515	protein binding	IPI	J:217902
Molecular Function	GO:0005515	protein binding	IPI	J:87180
Molecular Function	GO:0005515	protein binding	IPI	J:114917
Molecular Function	GO:0005515	protein binding	IPI	J:100200
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0097110	scaffold protein binding	ISO	J:155856
Molecular Function	GO:0038023	signaling receptor activity	ISO	J:155856
Molecular Function	GO:0000149	SNARE binding	ISO	J:155856
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	ISO	J:155856
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IBA	J:265628
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IMP	J:258046
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IDA	J:258046
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IDA	J:258046
Cellular Component	GO:0032281	AMPA glutamate receptor complex	ISO	J:155856
Cellular Component	GO:0032281	AMPA glutamate receptor complex	IBA	J:265628
Cellular Component	GO:0032281	AMPA glutamate receptor complex	IDA	J:100200
Cellular Component	GO:0032281	AMPA glutamate receptor complex	IDA	J:188364
Cellular Component	GO:0032279	asymmetric synapse	ISO	J:155856
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0030425	dendrite	IDA	J:260353
Cellular Component	GO:0032839	dendrite cytoplasm	ISO	J:155856
Cellular Component	GO:0032590	dendrite membrane	ISO	J:155856
Cellular Component	GO:0043198	dendritic shaft	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	IBA	J:265628
Cellular Component	GO:0044327	dendritic spine head	ISO	J:155856
Cellular Component	GO:0044326	dendritic spine neck	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:111556
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:105497
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:105497
Cellular Component	GO:0030426	growth cone	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:87180
Cellular Component	GO:0016020	membrane	IDA	J:114917
Cellular Component	GO:0016020	membrane	IDA	J:132191
Cellular Component	GO:0016020	membrane	IDA	J:132191
Cellular Component	GO:0043005	neuron projection	IDA	J:173402
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0043204	perikaryon	ISO	J:155856
Cellular Component	GO:0099544	perisynaptic space	IDA	J:260353
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:294276
Cellular Component	GO:0014069	postsynaptic density	IDA	J:96801
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0098839	postsynaptic density membrane	ISO	J:155856
Cellular Component	GO:0098839	postsynaptic density membrane	IBA	J:265628
Cellular Component	GO:0098839	postsynaptic density membrane	IDA	J:260353
Cellular Component	GO:0098839	postsynaptic density membrane	IDA	J:105497
Cellular Component	GO:0098839	postsynaptic density membrane	IDA	J:105497
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:144717
Cellular Component	GO:0098793	presynapse	ISO	J:155856
Cellular Component	GO:0048787	presynaptic active zone membrane	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	ISO	J:155856
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:258046
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IMP	J:258046
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:258046
Cellular Component	GO:0036477	somatodendritic compartment	IDA	J:135974
Cellular Component	GO:0106033	spine synapse	ISO	J:155856
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0045202	synapse	IDA	J:188364
Cellular Component	GO:0097060	synaptic membrane	IDA	J:217902
Cellular Component	GO:0008021	synaptic vesicle	IDA	J:160616
Cellular Component	GO:0030672	synaptic vesicle membrane	ISO	J:155856
Cellular Component	GO:0030672	synaptic vesicle membrane	IDA	J:260353
Cellular Component	GO:0043195	terminal bouton	ISO	J:155856
Biological Process	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus	ISO	J:155856
Biological Process	GO:1905430	cellular response to glycine	ISO	J:155856
Biological Process	GO:0007268	chemical synaptic transmission	ISO	J:155856
Biological Process	GO:0007268	chemical synaptic transmission	IDA	J:87180
Biological Process	GO:0045184	establishment of protein localization	ISO	J:155856
Biological Process	GO:0035235	ionotropic glutamate receptor signaling pathway	ISO	J:164563
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IBA	J:265628
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:72247
Biological Process	GO:0050806	positive regulation of synaptic transmission	ISO	J:155856
Biological Process	GO:0051262	protein tetramerization	ISO	J:155856
Biological Process	GO:0031623	receptor internalization	ISO	J:155856
Biological Process	GO:0001919	regulation of receptor recycling	ISO	J:155856
Biological Process	GO:0051966	regulation of synaptic transmission, glutamatergic	ISO	J:155856
Biological Process	GO:0035249	synaptic transmission, glutamatergic	IBA	J:265628