GO Annotations Graph

• Symbol: Gapdh
• Name: glyceraldehyde-3-phosphate dehydrogenase
• ID: MGI:95640

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019828	aspartic-type endopeptidase inhibitor activity	ISO	J:164563
Molecular Function	GO:0097718	disordered domain specific binding	ISO	J:164563
Molecular Function	GO:0019899	enzyme binding	IPI	J:182483
Molecular Function	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	ISO	J:155856
Molecular Function	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	IDA	J:182483
Molecular Function	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	IBA	J:265628
Molecular Function	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	IDA	J:5628
Molecular Function	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	IDA	J:246721
Molecular Function	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	IDA	J:246721
Molecular Function	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	IDA	J:246721
Molecular Function	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	IMP	J:95517
Molecular Function	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	IMP	J:15477
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0008017	microtubule binding	ISO	J:155856
Molecular Function	GO:0051287	NAD binding	IEA	J:72247
Molecular Function	GO:0050661	NADP binding	IEA	J:72247
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	IEA	J:72247
Molecular Function	GO:0035605	peptidyl-cysteine S-nitrosylase activity	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:150861
Molecular Function	GO:0005515	protein binding	IPI	J:322380
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IDA	J:151441
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:173639
Cellular Component	GO:0005737	cytoplasm	IDA	J:130677
Cellular Component	GO:0005737	cytoplasm	IDA	J:92551
Cellular Component	GO:0005737	cytoplasm	IDA	J:142120
Cellular Component	GO:0005737	cytoplasm	IDA	J:142671
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9631076
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9631080
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005829	cytosol	IDA	J:211907
Cellular Component	GO:0005829	cytosol	IDA	J:317783
Cellular Component	GO:0005829	cytosol	ISO	J:201969
Cellular Component	GO:0005829	cytosol	IDA	J:172256
Cellular Component	GO:0005829	cytosol	IDA	J:204025
Cellular Component	GO:0005829	cytosol	IDA	J:211907
Cellular Component	GO:0097452	GAIT complex	ISO	J:164563
Cellular Component	GO:0097452	GAIT complex	IDA	J:192858
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0031906	late endosome lumen	TAS	Reactome:R-MMU-9631080
Cellular Component	GO:0005811	lipid droplet	ISO	J:164563
Cellular Component	GO:0015630	microtubule cytoskeleton	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Cellular Component	GO:0031965	nuclear membrane	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:142120
Cellular Component	GO:0099092	postsynaptic density, intracellular component	ISO	J:155856
Cellular Component	GO:1990904	ribonucleoprotein complex	ISO	J:164563
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	ISO	J:155856
Biological Process	GO:0019933	cAMP-mediated signaling	ISO	J:155856
Biological Process	GO:0061621	canonical glycolysis	IMP	J:319895
Biological Process	GO:0061621	canonical glycolysis	IMP	J:318707
Biological Process	GO:0061621	canonical glycolysis	IDA	J:82180
Biological Process	GO:0005975	carbohydrate metabolic process	ISO	J:155856
Biological Process	GO:0071346	cellular response to type II interferon	ISO	J:164563
Biological Process	GO:0050832	defense response to fungus	ISO	J:164563
Biological Process	GO:0006094	gluconeogenesis	ISO	J:155856
Biological Process	GO:0006094	gluconeogenesis	IDA	J:246721
Biological Process	GO:0006094	gluconeogenesis	IDA	J:246721
Biological Process	GO:0006094	gluconeogenesis	IDA	J:246721
Biological Process	GO:0006006	glucose metabolic process	IEA	J:72247
Biological Process	GO:0006096	glycolytic process	ISO	J:155856
Biological Process	GO:0006096	glycolytic process	IBA	J:265628
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0051873	killing by host of symbiont cells	ISO	J:164563
Biological Process	GO:0031640	killing of cells of another organism	ISO	J:164563
Biological Process	GO:0000226	microtubule cytoskeleton organization	ISO	J:155856
Biological Process	GO:0007275	multicellular organism development	IMP	J:15477
Biological Process	GO:0010951	negative regulation of endopeptidase activity	ISO	J:164563
Biological Process	GO:0017148	negative regulation of translation	ISO	J:164563
Biological Process	GO:0017148	negative regulation of translation	IDA	J:192858
Biological Process	GO:1905460	negative regulation of vascular associated smooth muscle cell apoptotic process	ISO	J:155856
Biological Process	GO:0051402	neuron apoptotic process	ISO	J:155856
Biological Process	GO:0035606	peptidyl-cysteine S-trans-nitrosylation	ISO	J:155856
Biological Process	GO:0001819	positive regulation of cytokine production	ISO	J:164563
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0032481	positive regulation of type I interferon production	ISO	J:164563
Biological Process	GO:0050821	protein stabilization	ISO	J:155856
Biological Process	GO:0006417	regulation of translation	IEA	J:60000
Biological Process	GO:0060359	response to ammonium ion	ISO	J:155856