GO Annotations Graph

• Symbol: Mecom
• Name: MDS1 and EVI1 complex locus
• ID: MGI:95457

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IDA	J:156086
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IMP	J:99332
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:156032
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:99332
Molecular Function	GO:0046974	histone H3K9 methyltransferase activity	IDA	J:269562
Molecular Function	GO:0140948	histone H3K9 monomethyltransferase activity	IEA	J:72245
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008168	methyltransferase activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:138307
Molecular Function	GO:0005515	protein binding	IPI	J:182611
Molecular Function	GO:0005515	protein binding	IPI	J:138367
Molecular Function	GO:0005515	protein binding	IPI	J:138367
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:99332
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IMP	J:239216
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0000118	histone deacetylase complex	ISO	J:164563
Cellular Component	GO:0016607	nuclear speck	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:138307
Cellular Component	GO:0005634	nucleus	IDA	J:156086
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0035115	embryonic forelimb morphogenesis	IMP	J:113445
Biological Process	GO:0035115	embryonic forelimb morphogenesis	IMP	J:113445
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	IMP	J:113445
Biological Process	GO:0030900	forebrain development	IMP	J:113445
Biological Process	GO:0071425	hematopoietic stem cell proliferation	IMP	J:99332
Biological Process	GO:0070828	heterochromatin organization	IMP	J:269562
Biological Process	GO:0001701	in utero embryonic development	IMP	J:113445
Biological Process	GO:0006954	inflammatory response	IMP	J:113445
Biological Process	GO:0098727	maintenance of cell number	IGI	J:213153
Biological Process	GO:0032259	methylation	IEA	J:60000
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:138307
Biological Process	GO:0046329	negative regulation of JNK cascade	ISO	J:164563
Biological Process	GO:0043069	negative regulation of programmed cell death	ISO	J:164563
Biological Process	GO:0001780	neutrophil homeostasis	IMP	J:113445
Biological Process	GO:0060039	pericardium development	IMP	J:113445
Biological Process	GO:0090336	positive regulation of brown fat cell differentiation	IMP	J:213153
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:99332
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:99332
Biological Process	GO:0009791	post-embryonic development	IMP	J:113445
Biological Process	GO:0051726	regulation of cell cycle	ISO	J:164563
Biological Process	GO:1902033	regulation of hematopoietic stem cell proliferation	IMP	J:99332
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0009617	response to bacterium	IMP	J:113445
Biological Process	GO:0072197	ureter morphogenesis	IGI	J:174353
Biological Process	GO:0072197	ureter morphogenesis	IGI	J:174353
Biological Process	GO:0072197	ureter morphogenesis	IGI	J:174353
Biological Process	GO:0072197	ureter morphogenesis	IGI	J:174353