GO Annotations Graph

• Symbol: Stx4a
• Name: syntaxin 4A (placental)
• ID: MGI:893577

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:245361
Molecular Function	GO:0005515	protein binding	IPI	J:140958
Molecular Function	GO:0005515	protein binding	IPI	J:146942
Molecular Function	GO:0005515	protein binding	IPI	J:248246
Molecular Function	GO:0005515	protein binding	IPI	J:161112
Molecular Function	GO:0005515	protein binding	IPI	J:140958
Molecular Function	GO:0005515	protein binding	IPI	J:151132
Molecular Function	GO:0005515	protein binding	IPI	J:91698
Molecular Function	GO:0005515	protein binding	IPI	J:151132
Molecular Function	GO:0005515	protein binding	IPI	J:79240
Molecular Function	GO:0005515	protein binding	IPI	J:137704
Molecular Function	GO:0005515	protein binding	IPI	J:55848
Molecular Function	GO:0005515	protein binding	IPI	J:124940
Molecular Function	GO:0031267	small GTPase binding	ISO	J:155856
Molecular Function	GO:0005484	SNAP receptor activity	ISO	J:155856
Molecular Function	GO:0005484	SNAP receptor activity	IBA	J:265628
Molecular Function	GO:0000149	SNARE binding	ISO	J:155856
Molecular Function	GO:0000149	SNARE binding	IPI	J:161112
Molecular Function	GO:0000149	SNARE binding	IBA	J:265628
Molecular Function	GO:0030507	spectrin binding	ISO	J:155856
Molecular Function	GO:0016230	sphingomyelin phosphodiesterase activator activity	ISO	J:164563
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:155856
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:164563
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:139769
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IDA	J:209479
Cellular Component	GO:0005737	cytoplasm	IDA	J:91698
Cellular Component	GO:0043197	dendritic spine	ISO	J:164563
Cellular Component	GO:0012505	endomembrane system	IBA	J:265628
Cellular Component	GO:0005768	endosome	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:164563
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:326647
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:326647
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:326647
Cellular Component	GO:0030027	lamellipodium	ISO	J:164563
Cellular Component	GO:0043219	lateral loop	IDA	J:159103
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0035749	myelin sheath adaxonal region	IDA	J:159103
Cellular Component	GO:0032589	neuron projection membrane	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IDA	J:140958
Cellular Component	GO:0045335	phagocytic vesicle	IDA	J:143718
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-1449573
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IPI	J:137704
Cellular Component	GO:0005886	plasma membrane	IDA	J:91698
Cellular Component	GO:0005886	plasma membrane	IDA	J:137704
Cellular Component	GO:0005886	plasma membrane	IDA	J:182176
Cellular Component	GO:0098794	postsynapse	ISO	J:164563
Cellular Component	GO:0098794	postsynapse	IMP	J:326647
Cellular Component	GO:0098794	postsynapse	IDA	J:326647
Cellular Component	GO:0098794	postsynapse	IDA	J:326647
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0042383	sarcolemma	ISO	J:155856
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	ISO	J:155856
Cellular Component	GO:0031201	SNARE complex	ISO	J:155856
Cellular Component	GO:0031201	SNARE complex	ISO	J:164563
Cellular Component	GO:0031201	SNARE complex	IBA	J:265628
Cellular Component	GO:0031201	SNARE complex	IDA	J:137704
Cellular Component	GO:0036477	somatodendritic compartment	ISO	J:164563
Cellular Component	GO:0042581	specific granule	ISO	J:164563
Cellular Component	GO:0000322	storage vacuole	IDA	J:182176
Cellular Component	GO:0045202	synapse	ISO	J:164563
Cellular Component	GO:0005802	trans-Golgi network	IDA	J:140958
Biological Process	GO:0034599	cellular response to oxidative stress	ISO	J:164563
Biological Process	GO:0071346	cellular response to type II interferon	IDA	J:143718
Biological Process	GO:1903575	cornified envelope assembly	ISO	J:164563
Biological Process	GO:0098967	exocytic insertion of neurotransmitter receptor to postsynaptic membrane	ISO	J:155856
Biological Process	GO:0006887	exocytosis	IBA	J:265628
Biological Process	GO:0006886	intracellular protein transport	IBA	J:265628
Biological Process	GO:0060291	long-term synaptic potentiation	ISO	J:164563
Biological Process	GO:0061025	membrane fusion	ISO	J:155856
Biological Process	GO:0006836	neurotransmitter transport	IEA	J:60000
Biological Process	GO:0048284	organelle fusion	ISO	J:164563
Biological Process	GO:0043085	positive regulation of catalytic activity	ISO	J:164563
Biological Process	GO:0045785	positive regulation of cell adhesion	ISO	J:164563
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0050921	positive regulation of chemotaxis	ISO	J:164563
Biological Process	GO:0043311	positive regulation of eosinophil degranulation	ISO	J:164563
Biological Process	GO:0002639	positive regulation of immunoglobulin production	ISO	J:164563
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	ISO	J:164563
Biological Process	GO:2000010	positive regulation of protein localization to cell surface	ISO	J:164563
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	ISO	J:164563
Biological Process	GO:0034394	protein localization to cell surface	ISO	J:155856
Biological Process	GO:0065003	protein-containing complex assembly	ISO	J:155856
Biological Process	GO:0017157	regulation of exocytosis	ISO	J:164563
Biological Process	GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors	ISO	J:164563
Biological Process	GO:0035493	SNARE complex assembly	IDA	J:209479
Biological Process	GO:0016081	synaptic vesicle docking	ISO	J:155856
Biological Process	GO:0016079	synaptic vesicle exocytosis	TAS	J:79240
Biological Process	GO:0048278	vesicle docking	IBA	J:265628
Biological Process	GO:0006906	vesicle fusion	IBA	J:265628
Biological Process	GO:0016192	vesicle-mediated transport	IEA	J:72247
Biological Process	GO:0099003	vesicle-mediated transport in synapse	ISO	J:155856