GO Annotations Graph

• Symbol: Ank3
• Name: ankyrin 3, epithelial
• ID: MGI:88026

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0045296	cadherin binding	ISO	J:155856
Molecular Function	GO:0008092	cytoskeletal protein binding	ISO	J:155856
Molecular Function	GO:0140031	phosphorylation-dependent protein binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:165334
Molecular Function	GO:0005515	protein binding	IPI	J:97449
Molecular Function	GO:0005515	protein binding	IPI	J:165334
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	ISO	J:155856
Molecular Function	GO:0030507	spectrin binding	ISO	J:155856
Molecular Function	GO:0005200	structural constituent of cytoskeleton	ISO	J:164563
Molecular Function	GO:0044325	transmembrane transporter binding	IPI	J:217265
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:155856
Molecular Function	GO:0044325	transmembrane transporter binding	IBA	J:265628
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0030424	axon	IDA	J:93895
Cellular Component	GO:0043194	axon initial segment	IMP	J:266113
Cellular Component	GO:0043194	axon initial segment	ISO	J:164563
Cellular Component	GO:0043194	axon initial segment	IDA	J:184964
Cellular Component	GO:0043194	axon initial segment	IDA	J:240366
Cellular Component	GO:0043194	axon initial segment	ISO	J:155856
Cellular Component	GO:0043194	axon initial segment	IBA	J:265628
Cellular Component	GO:0043194	axon initial segment	IDA	J:228724
Cellular Component	GO:0043194	axon initial segment	IDA	J:165334
Cellular Component	GO:0009925	basal plasma membrane	ISO	J:164563
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:164563
Cellular Component	GO:0005923	bicellular tight junction	ISO	J:164563
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0043034	costamere	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0014704	intercalated disc	ISO	J:155856
Cellular Component	GO:0014704	intercalated disc	IDA	J:239053
Cellular Component	GO:0014704	intercalated disc	IDA	J:165334
Cellular Component	GO:0016328	lateral plasma membrane	ISO	J:164563
Cellular Component	GO:0005764	lysosome	IEA	J:60000
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0016020	membrane	IDA	J:26898
Cellular Component	GO:0031594	neuromuscular junction	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0033268	node of Ranvier	IDA	J:259112
Cellular Component	GO:0033268	node of Ranvier	ISO	J:155856
Cellular Component	GO:0033268	node of Ranvier	IDA	J:184964
Cellular Component	GO:0033270	paranode region of axon	IDA	J:166099
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0042383	sarcolemma	ISO	J:164563
Cellular Component	GO:0042383	sarcolemma	ISO	J:155856
Cellular Component	GO:0016529	sarcoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0014731	spectrin-associated cytoskeleton	ISO	J:155856
Cellular Component	GO:0045202	synapse	IBA	J:265628
Cellular Component	GO:0045202	synapse	IDA	J:76455
Cellular Component	GO:0030315	T-tubule	ISO	J:155856
Cellular Component	GO:0030018	Z disc	ISO	J:155856
Biological Process	GO:0008089	anterograde axonal transport	ISO	J:155856
Biological Process	GO:0061564	axon development	ISO	J:155856
Biological Process	GO:0007411	axon guidance	IMP	J:93895
Biological Process	GO:0007409	axonogenesis	IMP	J:184964
Biological Process	GO:0071286	cellular response to magnesium ion	IMP	J:217265
Biological Process	GO:0045162	clustering of voltage-gated sodium channels	ISO	J:155856
Biological Process	GO:0045184	establishment of protein localization	ISO	J:164563
Biological Process	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity	ISO	J:155856
Biological Process	GO:0043001	Golgi to plasma membrane protein transport	ISO	J:164563
Biological Process	GO:0010960	magnesium ion homeostasis	IMP	J:217265
Biological Process	GO:0032507	maintenance of protein location in cell	ISO	J:155856
Biological Process	GO:0072660	maintenance of protein location in plasma membrane	ISO	J:164563
Biological Process	GO:0071709	membrane assembly	ISO	J:164563
Biological Process	GO:0071709	membrane assembly	ISO	J:155856
Biological Process	GO:0000281	mitotic cytokinesis	ISO	J:164563
Biological Process	GO:1902260	negative regulation of delayed rectifier potassium channel activity	IMP	J:217265
Biological Process	GO:1902260	negative regulation of delayed rectifier potassium channel activity	IBA	J:265628
Biological Process	GO:0045806	negative regulation of endocytosis	ISO	J:155856
Biological Process	GO:0019228	neuronal action potential	IMP	J:51377
Biological Process	GO:0019228	neuronal action potential	IBA	J:265628
Biological Process	GO:0007009	plasma membrane organization	ISO	J:164563
Biological Process	GO:0045760	positive regulation of action potential	TAS	J:106271
Biological Process	GO:2001259	positive regulation of cation channel activity	ISO	J:155856
Biological Process	GO:0010650	positive regulation of cell communication by electrical coupling	ISO	J:155856
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:155856
Biological Process	GO:0034112	positive regulation of homotypic cell-cell adhesion	ISO	J:155856
Biological Process	GO:1900827	positive regulation of membrane depolarization during cardiac muscle cell action potential	ISO	J:155856
Biological Process	GO:0045838	positive regulation of membrane potential	ISO	J:155856
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	ISO	J:155856
Biological Process	GO:0090314	positive regulation of protein targeting to membrane	ISO	J:155856
Biological Process	GO:2000651	positive regulation of sodium ion transmembrane transporter activity	ISO	J:155856
Biological Process	GO:0010765	positive regulation of sodium ion transport	ISO	J:155856
Biological Process	GO:0099612	protein localization to axon	ISO	J:155856
Biological Process	GO:0099612	protein localization to axon	IMP	J:228724
Biological Process	GO:0072659	protein localization to plasma membrane	IDA	J:184964
Biological Process	GO:0072659	protein localization to plasma membrane	ISO	J:164563
Biological Process	GO:0072659	protein localization to plasma membrane	IMP	J:106271
Biological Process	GO:0072659	protein localization to plasma membrane	IMP	J:124649
Biological Process	GO:0072659	protein localization to plasma membrane	ISO	J:155856
Biological Process	GO:0043266	regulation of potassium ion transport	ISO	J:155856
Biological Process	GO:1903533	regulation of protein targeting	ISO	J:155856
Biological Process	GO:0007165	signal transduction	IEA	J:72247
Biological Process	GO:0050808	synapse organization	IMP	J:93895