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GO Annotations Graph
Symbol
Name
ID
Ddx58
DEAD/H box helicase 58
MGI:2442858

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005524ATP bindingIEAJ:60000
Molecular FunctionGO:0005524ATP bindingIEAJ:72247
Molecular FunctionGO:0003677DNA bindingIEAJ:72247
Molecular FunctionGO:0003690double-stranded DNA bindingIDAJ:145965
Molecular FunctionGO:0003725double-stranded RNA bindingISOJ:164563
Molecular FunctionGO:0003725double-stranded RNA bindingIDAJ:182522
Molecular FunctionGO:0003725double-stranded RNA bindingIDAJ:186390
Molecular FunctionGO:0004386helicase activityIEAJ:60000
Molecular FunctionGO:0016787hydrolase activityIEAJ:72247
Molecular FunctionGO:0016787hydrolase activityIEAJ:60000
Molecular FunctionGO:0016817hydrolase activity, acting on acid anhydridesIEAJ:72247
Molecular FunctionGO:0042802identical protein bindingISOJ:164563
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0005515protein bindingIPIJ:175771
Molecular FunctionGO:0005515protein bindingIPIJ:193456
Molecular FunctionGO:0003723RNA bindingIEAJ:60000
Molecular FunctionGO:0003727single-stranded RNA bindingISOJ:164563
Molecular FunctionGO:0003727single-stranded RNA bindingIDAJ:182522
Molecular FunctionGO:0008270zinc ion bindingISOJ:164563
Cellular ComponentGO:0015629actin cytoskeletonISOJ:164563
Cellular ComponentGO:0005923bicellular tight junctionISOJ:164563
Cellular ComponentGO:0030054cell junctionIEAJ:60000
Cellular ComponentGO:0042995cell projectionIEAJ:60000
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0005856cytoskeletonIEAJ:60000
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0005886plasma membraneIEAJ:60000
Cellular ComponentGO:0032587ruffle membraneISOJ:164563
Biological ProcessGO:0051607defense response to virusIEAJ:60000
Biological ProcessGO:0009597detection of virusISOJ:164563
Biological ProcessGO:0002376immune system processIEAJ:60000
Biological ProcessGO:0045087innate immune responseIMPJ:183219
Biological ProcessGO:0045087innate immune responseISOJ:164563
Biological ProcessGO:0002230positive regulation of defense response to virus by hostISOJ:164563
Biological ProcessGO:0010628positive regulation of gene expressionISOJ:164563
Biological ProcessGO:0032725positive regulation of granulocyte macrophage colony-stimulating factor productionISOJ:164563
Biological ProcessGO:0032727positive regulation of interferon-alpha productionISOJ:164563
Biological ProcessGO:0032728positive regulation of interferon-beta productionISOJ:164563
Biological ProcessGO:0032728positive regulation of interferon-beta productionIMPJ:183219
Biological ProcessGO:0032755positive regulation of interleukin-6 productionISOJ:164563
Biological ProcessGO:0032757positive regulation of interleukin-8 productionISOJ:164563
Biological ProcessGO:0042993positive regulation of transcription factor import into nucleusISOJ:164563
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterISOJ:164563
Biological ProcessGO:0030334regulation of cell migrationISOJ:164563
Biological ProcessGO:0043330response to exogenous dsRNAIMPJ:173994
Biological ProcessGO:0009615response to virusIMPJ:183219
Biological ProcessGO:0039529RIG-I signaling pathwayISOJ:164563


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/09/2022
MGI 6.21
The Jackson Laboratory