GO Annotations Graph

• Symbol: Rab7b
• Name: RAB7B, member RAS oncogene family
• ID: MGI:2442295

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005525	GTP binding	IEA	J:60000
Molecular Function	GO:0005525	GTP binding	IEA	J:72247
Molecular Function	GO:0003924	GTPase activity	IEA	J:72247
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0005770	late endosome	IDA	J:145405
Cellular Component	GO:0005770	late endosome	ISO	J:164563
Cellular Component	GO:0005770	late endosome	IDA	J:151709
Cellular Component	GO:0005770	late endosome	IBA	J:265628
Cellular Component	GO:0005764	lysosome	IDA	J:151709
Cellular Component	GO:0005764	lysosome	ISO	J:164563
Cellular Component	GO:0005764	lysosome	IDA	J:145405
Cellular Component	GO:0005764	lysosome	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0045335	phagocytic vesicle	ISO	J:164563
Cellular Component	GO:0045335	phagocytic vesicle	IBA	J:265628
Cellular Component	GO:0045335	phagocytic vesicle	IDA	J:143718
Cellular Component	GO:0005802	trans-Golgi network	ISO	J:164563
Biological Process	GO:0071346	cellular response to type II interferon	IDA	J:143718
Biological Process	GO:0008333	endosome to lysosome transport	IBA	J:265628
Biological Process	GO:0034499	late endosome to Golgi transport	ISO	J:164563
Biological Process	GO:0034144	negative regulation of toll-like receptor 4 signaling pathway	IMP	J:145405
Biological Process	GO:0034164	negative regulation of toll-like receptor 9 signaling pathway	IMP	J:151709
Biological Process	GO:0090385	phagosome-lysosome fusion	IBA	J:265628
Biological Process	GO:0032755	positive regulation of interleukin-6 production	ISO	J:164563
Biological Process	GO:0045654	positive regulation of megakaryocyte differentiation	ISO	J:164563
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:0015031	protein transport	IEA	J:60000