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GO Annotations Graph
Symbol
Name
ID
Rapgef3
Rap guanine nucleotide exchange factor (GEF) 3
MGI:2441741

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0030552cAMP bindingISOJ:155856
Molecular FunctionGO:0005085guanyl-nucleotide exchange factor activityIDAJ:88364
Molecular FunctionGO:0044325ion channel bindingISOJ:155856
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0005515protein bindingIPIJ:197247
Molecular FunctionGO:0019904protein domain specific bindingISOJ:164563
Molecular FunctionGO:0017034Rap guanyl-nucleotide exchange factor activityISOJ:164563
Cellular ComponentGO:0045177apical part of cellISOJ:155856
Cellular ComponentGO:0043679axon terminusISOJ:155856
Cellular ComponentGO:0009925basal plasma membraneISOJ:155856
Cellular ComponentGO:1990794basolateral part of cellISOJ:155856
Cellular ComponentGO:0031526brush border membraneISOJ:155856
Cellular ComponentGO:0071944cell peripheryISOJ:155856
Cellular ComponentGO:0030864colocalizes_with
cortical actin cytoskeleton
ISOJ:164563
Cellular ComponentGO:0030864colocalizes_with
cortical actin cytoskeleton
ISOJ:155856
Cellular ComponentGO:0005737cytoplasmIEAJ:60000
Cellular ComponentGO:0070062extracellular exosomeISOJ:164563
Cellular ComponentGO:0030175filopodiumISOJ:164563
Cellular ComponentGO:0030175filopodiumISOJ:155856
Cellular ComponentGO:0030426growth coneISOJ:155856
Cellular ComponentGO:0030027lamellipodiumISOJ:164563
Cellular ComponentGO:0030027lamellipodiumISOJ:155856
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0005902microvillusISOJ:155856
Cellular ComponentGO:0005902microvillusISOJ:164563
Cellular ComponentGO:0043025neuronal cell bodyISOJ:155856
Cellular ComponentGO:0031090organelle membraneISOJ:155856
Cellular ComponentGO:0048471perinuclear region of cytoplasmISOJ:155856
Cellular ComponentGO:1990796photoreceptor cell terminal boutonISOJ:155856
Cellular ComponentGO:0005886colocalizes_with
plasma membrane
ISOJ:164563
Cellular ComponentGO:0005886colocalizes_with
plasma membrane
ISOJ:155856
Cellular ComponentGO:0097470ribbon synapseISOJ:155856
Cellular ComponentGO:1990795rod bipolar cell terminal boutonISOJ:155856
Biological ProcessGO:0001525angiogenesisIEAJ:60000
Biological ProcessGO:0071320cellular response to cAMPISOJ:164563
Biological ProcessGO:0061028establishment of endothelial barrierISOJ:164563
Biological ProcessGO:0035556intracellular signal transductionIEAJ:72247
Biological ProcessGO:0010667negative regulation of cardiac muscle cell apoptotic processISOJ:155856
Biological ProcessGO:0032966negative regulation of collagen biosynthetic processISOJ:155856
Biological ProcessGO:0034242negative regulation of syncytium formation by plasma membrane fusionISOJ:164563
Biological ProcessGO:2000251positive regulation of actin cytoskeleton reorganizationISOJ:155856
Biological ProcessGO:0045766positive regulation of angiogenesisISOJ:164563
Biological ProcessGO:1904427positive regulation of calcium ion transmembrane transportISOJ:155856
Biological ProcessGO:0045793positive regulation of cell sizeISOJ:155856
Biological ProcessGO:1904426positive regulation of GTP bindingISOJ:155856
Biological ProcessGO:0043547positive regulation of GTPase activityISOJ:164563
Biological ProcessGO:1904453positive regulation of hydrogen:potassium-exchanging ATPase activityISOJ:155856
Biological ProcessGO:0033138positive regulation of peptidyl-serine phosphorylationISOJ:164563
Biological ProcessGO:1901985positive regulation of protein acetylationISOJ:164563
Biological ProcessGO:0046827positive regulation of protein export from nucleusISOJ:164563
Biological ProcessGO:0001934positive regulation of protein phosphorylationISOJ:155856
Biological ProcessGO:0014911positive regulation of smooth muscle cell migrationISOJ:155856
Biological ProcessGO:0051496positive regulation of stress fiber assemblyISOJ:164563
Biological ProcessGO:0060143positive regulation of syncytium formation by plasma membrane fusionISOJ:164563
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterISOJ:155856
Biological ProcessGO:0032486Rap protein signal transductionISOJ:164563
Biological ProcessGO:2000249regulation of actin cytoskeleton reorganizationISOJ:164563
Biological ProcessGO:0007264small GTPase mediated signal transductionIEAJ:72247


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/10/2020
MGI 6.16
The Jackson Laboratory