GO Annotations Graph

• Symbol: Kdm1b
• Name: lysine (K)-specific demethylase 1B
• ID: MGI:2145261

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IBA	J:265628
Molecular Function	GO:0071949	FAD binding	ISO	J:164563
Molecular Function	GO:0140682	FAD-dependent H3K4me/H3K4me3 demethylase activity	ISO	J:164563
Molecular Function	GO:0140682	FAD-dependent H3K4me/H3K4me3 demethylase activity	ISO	J:164563
Molecular Function	GO:0140682	FAD-dependent H3K4me/H3K4me3 demethylase activity	IDA	J:151192
Molecular Function	GO:0140682	FAD-dependent H3K4me/H3K4me3 demethylase activity	IDA	J:152382
Molecular Function	GO:0050660	flavin adenine dinucleotide binding	IBA	J:265628
Molecular Function	GO:0050660	flavin adenine dinucleotide binding	IDA	J:151192
Molecular Function	GO:0042393	histone binding	ISO	J:164563
Molecular Function	GO:0032453	histone H3K4 demethylase activity	IDA	J:151192
Molecular Function	GO:0032453	histone H3K4 demethylase activity	IDA	J:152382
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0016491	oxidoreductase activity	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:187380
Molecular Function	GO:0008134	transcription factor binding	IBA	J:265628
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	IDA	J:151192
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0000786	nucleosome	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:152382
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0043046	DNA methylation involved in gamete generation	IMP	J:152382
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006349	regulation of gene expression by genomic imprinting	IMP	J:152382
Biological Process	GO:0045815	transcription initiation-coupled chromatin remodeling	ISO	J:164563