GO Annotations Graph

• Symbol: Mael
• Name: maelstrom spermatogenic transposon silencer
• ID: MGI:2138453

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:243444
Molecular Function	GO:0005515	protein binding	IPI	J:112036
Molecular Function	GO:0005515	protein binding	IPI	J:112036
Molecular Function	GO:0005515	protein binding	IPI	J:112036
Molecular Function	GO:0005515	protein binding	IPI	J:112036
Molecular Function	GO:0005515	protein binding	IPI	J:112036
Molecular Function	GO:0005515	protein binding	IPI	J:112036
Molecular Function	GO:0005515	protein binding	IPI	J:112036
Molecular Function	GO:0005515	protein binding	IPI	J:112036
Molecular Function	GO:0003723	RNA binding	IEA	J:60000
Molecular Function	GO:0043565	sequence-specific DNA binding	IBA	J:265628
Cellular Component	GO:0030849	autosome	IDA	J:112036
Cellular Component	GO:0000785	chromatin	IDA	J:112036
Cellular Component	GO:0033391	chromatoid body	IDA	J:112036
Cellular Component	GO:0005737	cytoplasm	IDA	J:140402
Cellular Component	GO:0005737	cytoplasm	IDA	J:112036
Cellular Component	GO:0005737	cytoplasm	IDA	J:112036
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-5606210
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-5606252
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-5606256
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-5629230
Cellular Component	GO:0001673	male germ cell nucleus	IDA	J:112036
Cellular Component	GO:0001673	male germ cell nucleus	IDA	J:140402
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5606256
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0043186	P granule	IBA	J:265628
Cellular Component	GO:0043186	P granule	IDA	J:112036
Cellular Component	GO:0043186	P granule	IDA	J:140402
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IDA	J:140402
Cellular Component	GO:0071547	piP-body	IDA	J:155865
Cellular Component	GO:0001741	XY body	IDA	J:112036
Biological Process	GO:0006915	apoptotic process	IMP	J:140402
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0000902	cell morphogenesis	IMP	J:140402
Biological Process	GO:0006974	DNA damage response	IMP	J:140402
Biological Process	GO:0043046	DNA methylation involved in gamete generation	IMP	J:155865
Biological Process	GO:0035234	ectopic germ cell programmed cell death	IMP	J:140402
Biological Process	GO:0009566	fertilization	IMP	J:140402
Biological Process	GO:0010467	gene expression	IMP	J:140402
Biological Process	GO:0007129	homologous chromosome pairing at meiosis	IMP	J:140402
Biological Process	GO:0007129	homologous chromosome pairing at meiosis	IMP	J:140402
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	IMP	J:140402
Biological Process	GO:0007140	male meiotic nuclear division	IBA	J:265628
Biological Process	GO:0007140	male meiotic nuclear division	IMP	J:140402
Biological Process	GO:0051321	meiotic cell cycle	IEA	J:60000
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:140402
Biological Process	GO:0051093	negative regulation of developmental process	IMP	J:140402
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IBA	J:265628
Biological Process	GO:0010629	negative regulation of gene expression	IMP	J:140402
Biological Process	GO:2000242	negative regulation of reproductive process	IMP	J:140402
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:140402
Biological Process	GO:0034587	piRNA processing	IMP	J:155865
Biological Process	GO:0034587	piRNA processing	IMP	J:140402
Biological Process	GO:0034587	piRNA processing	IBA	J:265628
Biological Process	GO:0060964	regulation of miRNA-mediated gene silencing	IEA	J:72247
Biological Process	GO:0046620	regulation of organ growth	IMP	J:140402
Biological Process	GO:0031047	RNA-mediated gene silencing	IMP	J:140402
Biological Process	GO:0007283	spermatogenesis	IBA	J:265628
Biological Process	GO:0007283	spermatogenesis	IMP	J:140402