GO Annotations Graph

• Symbol: Fam20c
• Name: FAM20C, golgi associated secretory pathway kinase
• ID: MGI:2136853

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005509	calcium ion binding	IDA	J:122675
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0030145	manganese ion binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0002020	protease binding	ISO	J:164563
Molecular Function	GO:0004672	protein kinase activity	ISO	J:164563
Molecular Function	GO:0043621	protein self-association	ISO	J:164563
Molecular Function	GO:0004674	protein serine/threonine kinase activity	ISO	J:164563
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IDA	J:222145
Molecular Function	GO:0004674	protein serine/threonine kinase activity	ISO	J:155856
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IBA	J:265628
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IDA	J:211241
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	HDA	J:221550
Cellular Component	GO:0005615	extracellular space	IDA	J:122675
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:222145
Cellular Component	GO:0000139	Golgi membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Biological Process	GO:0046034	ATP metabolic process	ISO	J:155856
Biological Process	GO:0031214	biomineral tissue development	ISO	J:164563
Biological Process	GO:0097187	dentinogenesis	IMP	J:186384
Biological Process	GO:0070166	enamel mineralization	IMP	J:186384
Biological Process	GO:0071895	odontoblast differentiation	IDA	J:122675
Biological Process	GO:0036179	osteoclast maturation	IMP	J:185208
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0030501	positive regulation of bone mineralization	IDA	J:185208
Biological Process	GO:0030501	positive regulation of bone mineralization	IDA	J:122675
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	IDA	J:185208
Biological Process	GO:0046777	protein autophosphorylation	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	ISO	J:155856
Biological Process	GO:0006468	protein phosphorylation	IDA	J:222145
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IBA	J:265628
Biological Process	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	IMP	J:185208
Biological Process	GO:0051174	regulation of phosphorus metabolic process	IMP	J:185208
Biological Process	GO:0001501	skeletal system development	IMP	J:186384
Biological Process	GO:0001501	skeletal system development	IMP	J:185208