Vangl2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Vangl2
VANGL planar cell polarity 2
MGI:2135272

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:169104
Molecular Function	GO:0005515	protein binding	IPI	J:197374
Molecular Function	GO:0005515	protein binding	IPI	J:187547
Molecular Function	GO:0005515	protein binding	IPI	J:168261
Molecular Function	GO:0005515	protein binding	IPI	J:95171
Molecular Function	GO:0005515	protein binding	IPI	J:95171
Molecular Function	GO:0005515	protein binding	IPI	J:108647
Molecular Function	GO:0005515	protein binding	IPI	J:145627
Molecular Function	GO:0005515	protein binding	IPI	J:217667
Molecular Function	GO:0005515	protein binding	IPI	J:163736
Molecular Function	GO:0005515	protein binding	IPI	J:152701
Molecular Function	GO:0005515	protein binding	IPI	J:95171
Molecular Function	GO:0005515	protein binding	IPI	J:205269
Molecular Function	GO:0005515	protein binding	IPI	J:217667
Cellular Component	GO:0090651	apical cytoplasm	IDA	J:222454
Cellular Component	GO:0090651	apical cytoplasm	IDA	J:222454
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:108647
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:108647
Cellular Component	GO:0016323	basolateral plasma membrane	IDA	J:168261
Cellular Component	GO:0071944	cell periphery	IDA	J:158680
Cellular Component	GO:0060187	cell pole	IDA	J:149821
Cellular Component	GO:0005911	cell-cell junction	IDA	J:168261
Cellular Component	GO:0005911	cell-cell junction	IDA	J:217667
Cellular Component	GO:0005911	cell-cell junction	IDA	J:122585
Cellular Component	GO:0005911	cell-cell junction	IDA	J:163736
Cellular Component	GO:0030134	COPII-coated ER to Golgi transport vesicle	IDA	J:158452
Cellular Component	GO:0016328	lateral plasma membrane	IDA	J:122585
Cellular Component	GO:0016328	lateral plasma membrane	IDA	J:161641
Cellular Component	GO:0016020	membrane	ISS	J:95171
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-4551566
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-4551572
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-4608838
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-4608842
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:205269
Cellular Component	GO:0005886	plasma membrane	IDA	J:116150
Cellular Component	GO:0005886	plasma membrane	IDA	J:158680
Cellular Component	GO:0001725	stress fiber	IDA	J:205269
Biological Process	GO:0009952	anterior/posterior pattern specification	IMP	J:145627
Biological Process	GO:0045176	apical protein localization	IMP	J:105752
Biological Process	GO:0045176	apical protein localization	IMP	J:108647
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	TAS	J:169941
Biological Process	GO:0060947	cardiac vascular smooth muscle cell differentiation	TAS	J:169941
Biological Process	GO:0035787	cell migration involved in kidney development	IMP	J:168261
Biological Process	GO:0090102	cochlea development	IGI	J:131308
Biological Process	GO:0090103	cochlea morphogenesis	IGI	J:165556
Biological Process	GO:0090103	cochlea morphogenesis	IMP	J:140886
Biological Process	GO:0090103	cochlea morphogenesis	IGI	J:122585
Biological Process	GO:0090103	cochlea morphogenesis	IMP	J:100861
Biological Process	GO:0090103	cochlea morphogenesis	IGI	J:142392
Biological Process	GO:0090103	cochlea morphogenesis	IGI	J:162624
Biological Process	GO:0060028	convergent extension involved in axis elongation	IMP	J:119920
Biological Process	GO:0022007	convergent extension involved in neural plate elongation	IMP	J:108512
Biological Process	GO:0022007	convergent extension involved in neural plate elongation	IGI	J:108512
Biological Process	GO:0022007	convergent extension involved in neural plate elongation	IMP	J:119920
Biological Process	GO:0060029	convergent extension involved in organogenesis	IGI	J:122585
Biological Process	GO:0048546	digestive tract morphogenesis	IGI	J:147041
Biological Process	GO:0048546	digestive tract morphogenesis	IGI	J:147041
Biological Process	GO:0048546	digestive tract morphogenesis	IGI	J:147041
Biological Process	GO:0036514	dopaminergic neuron axon guidance	IMP	J:166974
Biological Process	GO:0003347	epicardial cell to mesenchymal cell transition	TAS	J:169941
Biological Process	GO:0048105	establishment of body hair planar orientation	IMP	J:145627
Biological Process	GO:0090162	establishment of epithelial cell polarity	TAS	J:169941
Biological Process	GO:0001736	establishment of planar polarity	IMP	J:83127
Biological Process	GO:0001736	establishment of planar polarity	IMP	J:106431
Biological Process	GO:0001736	establishment of planar polarity	IBA	J:265628
Biological Process	GO:0001736	establishment of planar polarity	IGI	J:162624
Biological Process	GO:0090177	establishment of planar polarity involved in neural tube closure	IMP	J:140886
Biological Process	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	IMP	J:119451
Biological Process	GO:0032835	glomerulus development	IMP	J:166958
Biological Process	GO:0001942	hair follicle development	IMP	J:145627
Biological Process	GO:0001947	heart looping	IMP	J:74156
Biological Process	GO:0015012	heparan sulfate proteoglycan biosynthetic process	IMP	J:198639
Biological Process	GO:0060119	inner ear receptor cell development	IGI	J:165556
Biological Process	GO:0060122	inner ear receptor cell stereocilium organization	IGI	J:198639
Biological Process	GO:0060122	inner ear receptor cell stereocilium organization	IMP	J:140886
Biological Process	GO:0060122	inner ear receptor cell stereocilium organization	IGI	J:131308
Biological Process	GO:0060993	kidney morphogenesis	IMP	J:166958
Biological Process	GO:0060490	lateral sprouting involved in lung morphogenesis	IMP	J:159690
Biological Process	GO:0003149	membranous septum morphogenesis	IGI	J:165556
Biological Process	GO:0003149	membranous septum morphogenesis	IGI	J:165556
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0007275	multicellular organism development	IEA	J:72247
Biological Process	GO:0003150	muscular septum morphogenesis	IGI	J:165556
Biological Process	GO:0003150	muscular septum morphogenesis	IGI	J:165556
Biological Process	GO:0001843	neural tube closure	IGI	J:119920
Biological Process	GO:0001843	neural tube closure	IGI	J:91298
Biological Process	GO:0001843	neural tube closure	IMP	J:81365
Biological Process	GO:0001843	neural tube closure	IGI	J:119920
Biological Process	GO:0001843	neural tube closure	IGI	J:167834
Biological Process	GO:0001843	neural tube closure	IGI	J:85744
Biological Process	GO:0001843	neural tube closure	IGI	J:122585
Biological Process	GO:0001843	neural tube closure	IGI	J:198639
Biological Process	GO:0001843	neural tube closure	IMP	J:72911
Biological Process	GO:0001843	neural tube closure	IGI	J:158452
Biological Process	GO:0035567	non-canonical Wnt signaling pathway	IMP	J:149821
Biological Process	GO:1905515	non-motile cilium assembly	IGI	J:102697
Biological Process	GO:1905515	non-motile cilium assembly	IGI	J:102697
Biological Process	GO:0060488	orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis	IMP	J:159690
Biological Process	GO:0003148	outflow tract septum morphogenesis	TAS	J:169941
Biological Process	GO:0003402	planar cell polarity pathway involved in axis elongation	IGI	J:135313
Biological Process	GO:0003402	planar cell polarity pathway involved in axis elongation	IGI	J:135313
Biological Process	GO:0003402	planar cell polarity pathway involved in axis elongation	IGI	J:135313
Biological Process	GO:1904938	planar cell polarity pathway involved in axon guidance	IMP	J:166974
Biological Process	GO:0061346	planar cell polarity pathway involved in heart morphogenesis	IMP	J:205269
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IGI	J:165556
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IGI	J:163834
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IMP	J:108512
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IGI	J:142392
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IGI	J:165556
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IGI	J:162624
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IGI	J:135313
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IGI	J:163834
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IGI	J:135313
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IGI	J:108512
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IGI	J:135313
Biological Process	GO:0060489	planar dichotomous subdivision of terminal units involved in lung branching morphogenesis	IMP	J:159690
Biological Process	GO:0043507	positive regulation of JUN kinase activity	IGI	J:163736
Biological Process	GO:0043507	positive regulation of JUN kinase activity	IGI	J:163736
Biological Process	GO:0036342	post-anal tail morphogenesis	IMP	J:174196
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	IMP	J:159690
Biological Process	GO:0090175	regulation of establishment of planar polarity	IGI	J:147041
Biological Process	GO:0090175	regulation of establishment of planar polarity	IGI	J:147041
Biological Process	GO:0090175	regulation of establishment of planar polarity	IGI	J:147041
Biological Process	GO:0030111	regulation of Wnt signaling pathway	IMP	J:205269
Biological Process	GO:0007266	Rho protein signal transduction	IMP	J:159690
Biological Process	GO:0036515	serotonergic neuron axon guidance	IMP	J:166974
Biological Process	GO:0048103	somatic stem cell division	IMP	J:149821
Biological Process	GO:0035019	somatic stem cell population maintenance	IMP	J:149821
Biological Process	GO:0060071	Wnt signaling pathway, planar cell polarity pathway	IBA	J:265628
Biological Process	GO:0060071	Wnt signaling pathway, planar cell polarity pathway	IGI	J:152701
Biological Process	GO:0060071	Wnt signaling pathway, planar cell polarity pathway	IMP	J:100861
Biological Process	GO:0060071	Wnt signaling pathway, planar cell polarity pathway	IGI	J:122585
Biological Process	GO:0042060	wound healing	IGI	J:198639
Biological Process	GO:0042060	wound healing	IGI	J:162624
Biological Process	GO:0042060	wound healing	IGI	J:162624
Biological Process	GO:0042060	wound healing	IGI	J:162624
Biological Process	GO:0042060	wound healing	IGI	J:162624

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23