GO Annotations Graph

• Symbol: Mff
• Name: mitochondrial fission factor
• ID: MGI:1922984

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051020	GTPase binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:273332
Molecular Function	GO:0005515	protein binding	IPI	J:286525
Molecular Function	GO:0005515	protein binding	IPI	J:167998
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0031966	mitochondrial membrane	ISO	J:155856
Cellular Component	GO:0031966	mitochondrial membrane	ISO	J:164563
Cellular Component	GO:0005741	mitochondrial outer membrane	IDA	J:286525
Cellular Component	GO:0005741	mitochondrial outer membrane	ISO	J:164563
Cellular Component	GO:0005741	mitochondrial outer membrane	IDA	J:167998
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IDA	J:167950
Cellular Component	GO:0005777	peroxisome	IDA	J:167950
Cellular Component	GO:0005777	peroxisome	ISO	J:164563
Cellular Component	GO:0005777	peroxisome	IBA	J:265628
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0045202	synapse	IEA	J:60000
Cellular Component	GO:0008021	synaptic vesicle	ISO	J:155856
Cellular Component	GO:0030672	synaptic vesicle membrane	ISO	J:155856
Biological Process	GO:0000266	mitochondrial fission	IDA	J:286525
Biological Process	GO:0000266	mitochondrial fission	IMP	J:200469
Biological Process	GO:0043653	mitochondrial fragmentation involved in apoptotic process	ISO	J:164563
Biological Process	GO:0008053	mitochondrial fusion	ISO	J:164563
Biological Process	GO:0070584	mitochondrion morphogenesis	ISO	J:73065
Biological Process	GO:0016559	peroxisome fission	ISO	J:164563
Biological Process	GO:0010666	positive regulation of cardiac muscle cell apoptotic process	ISO	J:155856
Biological Process	GO:0090141	positive regulation of mitochondrial fission	ISO	J:155856
Biological Process	GO:0090141	positive regulation of mitochondrial fission	ISO	J:164563
Biological Process	GO:0090141	positive regulation of mitochondrial fission	IBA	J:265628
Biological Process	GO:0090314	positive regulation of protein targeting to membrane	ISO	J:164563
Biological Process	GO:0090200	positive regulation of release of cytochrome c from mitochondria	ISO	J:164563
Biological Process	GO:1900244	positive regulation of synaptic vesicle endocytosis	ISO	J:155856
Biological Process	GO:0006626	protein targeting to mitochondrion	ISO	J:155856
Biological Process	GO:0006626	protein targeting to mitochondrion	IDA	J:286525
Biological Process	GO:0006626	protein targeting to mitochondrion	ISO	J:164563
Biological Process	GO:0006626	protein targeting to mitochondrion	IBA	J:265628
Biological Process	GO:0010821	regulation of mitochondrion organization	ISO	J:164563
Biological Process	GO:1900063	regulation of peroxisome organization	ISO	J:164563
Biological Process	GO:0001836	release of cytochrome c from mitochondria	ISO	J:164563