GO Annotations Graph

• Symbol: Dhcr24
• Name: 24-dehydrocholesterol reductase
• ID: MGI:1922004

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0000246	delta24(24-1) sterol reductase activity	ISO	J:164563
Molecular Function	GO:0000246	delta24(24-1) sterol reductase activity	IBA	J:265628
Molecular Function	GO:0050614	delta24-sterol reductase activity	ISO	J:164563
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0071949	FAD binding	IEA	J:72247
Molecular Function	GO:0050660	flavin adenine dinucleotide binding	IEA	J:72247
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:72247
Molecular Function	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	ISO	J:71595
Molecular Function	GO:0042605	peptide antigen binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005856	cytoskeleton	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	IEA	J:60000
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Biological Process	GO:0042987	amyloid precursor protein catabolic process	IMP	J:105158
Biological Process	GO:0006695	cholesterol biosynthetic process	IMP	J:108495
Biological Process	GO:0006695	cholesterol biosynthetic process	IMP	J:129658
Biological Process	GO:0006695	cholesterol biosynthetic process	IMP	J:87402
Biological Process	GO:0006695	cholesterol biosynthetic process	ISO	J:71595
Biological Process	GO:0033489	cholesterol biosynthetic process via desmosterol	ISO	J:164563
Biological Process	GO:0008203	cholesterol metabolic process	IMP	J:105158
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0030539	male genitalia development	IMP	J:87402
Biological Process	GO:0061024	membrane organization	IMP	J:105158
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:0031639	plasminogen activation	IMP	J:105158
Biological Process	GO:0008104	protein localization	IMP	J:129658
Biological Process	GO:0008104	protein localization	IMP	J:105158
Biological Process	GO:0007265	Ras protein signal transduction	ISO	J:155856
Biological Process	GO:0043588	skin development	IMP	J:106756
Biological Process	GO:0006694	steroid biosynthetic process	IEA	J:60000
Biological Process	GO:0008202	steroid metabolic process	ISO	J:155856
Biological Process	GO:0008202	steroid metabolic process	IBA	J:265628
Biological Process	GO:0016126	sterol biosynthetic process	IEA	J:60000
Biological Process	GO:0016125	sterol metabolic process	IMP	J:87402
Biological Process	GO:0009888	tissue development	ISO	J:164563
Biological Process	GO:0009888	tissue development	IMP	J:87402
Biological Process	GO:0009888	tissue development	IMP	J:87402