GO Annotations Graph

• Symbol: Bag6
• Name: BCL2-associated athanogene 6
• ID: MGI:1919439

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0030544	Hsp70 protein binding	IPI	J:139505
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0051787	misfolded protein binding	ISO	J:164563
Molecular Function	GO:0051787	misfolded protein binding	IBA	J:265628
Molecular Function	GO:0031593	polyubiquitin modification-dependent protein binding	IDA	J:168161
Molecular Function	GO:0031593	polyubiquitin modification-dependent protein binding	IBA	J:265628
Molecular Function	GO:0070628	proteasome binding	IDA	J:168161
Molecular Function	GO:0005515	protein binding	IPI	J:131590
Molecular Function	GO:0005515	protein binding	IPI	J:114108
Molecular Function	GO:0005515	protein binding	IPI	J:182961
Molecular Function	GO:0043022	ribosome binding	ISO	J:164563
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:164563
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Molecular Function	GO:1990381	ubiquitin-specific protease binding	ISO	J:164563
Cellular Component	GO:0071818	BAT3 complex	ISO	J:164563
Cellular Component	GO:0071818	BAT3 complex	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISS	J:55895
Cellular Component	GO:0005829	cytosol	NAS	J:320131
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IDA	J:131590
Cellular Component	GO:0070062	extracellular exosome	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:182961
Biological Process	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	TAS	J:168161
Biological Process	GO:0006915	apoptotic process	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	RCA	J:84168
Biological Process	GO:0007420	brain development	IMP	J:119857
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0061857	endoplasmic reticulum stress-induced pre-emptive quality control	ISO	J:164563
Biological Process	GO:0071712	ER-associated misfolded protein catabolic process	ISO	J:164563
Biological Process	GO:0002429	immune response-activating cell surface receptor signaling pathway	ISO	J:164563
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0018393	internal peptidyl-lysine acetylation	ISO	J:164563
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	ISO	J:164563
Biological Process	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	IMP	J:131590
Biological Process	GO:0001822	kidney development	IMP	J:119857
Biological Process	GO:0030324	lung development	IMP	J:119857
Biological Process	GO:1904378	maintenance of unfolded protein involved in ERAD pathway	ISO	J:164563
Biological Process	GO:0030101	natural killer cell activation	ISO	J:164563
Biological Process	GO:0043066	negative regulation of apoptotic process	IGI	J:182961
Biological Process	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	IMP	J:139505
Biological Process	GO:0045861	negative regulation of proteolysis	IMP	J:131590
Biological Process	GO:1904294	positive regulation of ERAD pathway	ISO	J:164563
Biological Process	GO:0006620	post-translational protein targeting to endoplasmic reticulum membrane	ISO	J:164563
Biological Process	GO:0010498	proteasomal protein catabolic process	ISO	J:164563
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	IMP	J:233169
Biological Process	GO:0050821	protein stabilization	IMP	J:139505
Biological Process	GO:0050821	protein stabilization	IMP	J:131590
Biological Process	GO:0042981	regulation of apoptotic process	IMP	J:119857
Biological Process	GO:0042981	regulation of apoptotic process	RCA	J:84168
Biological Process	GO:0045995	regulation of embryonic development	IMP	J:119857
Biological Process	GO:0031647	regulation of protein stability	ISO	J:164563
Biological Process	GO:0007283	spermatogenesis	IMP	J:139505
Biological Process	GO:0007130	synaptonemal complex assembly	IMP	J:139505
Biological Process	GO:0071816	tail-anchored membrane protein insertion into ER membrane	ISO	J:164563
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	ISO	J:164563
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	IBA	J:265628
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	IMP	J:168161