GO Annotations Graph

• Symbol: Ctc1
• Name: CTS telomere maintenance complex component 1
• ID: MGI:1916214

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0098505	G-rich strand telomeric DNA binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:159131
Molecular Function	GO:0003697	single-stranded DNA binding	IDA	J:159131
Molecular Function	GO:0003697	single-stranded DNA binding	IBA	J:265628
Molecular Function	GO:0042162	telomeric DNA binding	ISO	J:164563
Molecular Function	GO:0042162	telomeric DNA binding	IBA	J:265628
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000781	chromosome, telomeric region	ISO	J:164563
Cellular Component	GO:0000781	chromosome, telomeric region	IDA	J:159049
Cellular Component	GO:1990879	CST complex	IDA	J:159049
Cellular Component	GO:1990879	CST complex	ISO	J:164563
Cellular Component	GO:1990879	CST complex	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:159049
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:159131
Biological Process	GO:0048539	bone marrow development	IMP	J:184809
Biological Process	GO:0051276	chromosome organization	IMP	J:184809
Biological Process	GO:0006974	DNA damage response	IMP	J:184809
Biological Process	GO:0071425	hematopoietic stem cell proliferation	IMP	J:184809
Biological Process	GO:0035264	multicellular organism growth	IMP	J:184809
Biological Process	GO:0032211	negative regulation of telomere maintenance via telomerase	ISO	J:164563
Biological Process	GO:0045740	positive regulation of DNA replication	IDA	J:159131
Biological Process	GO:0045740	positive regulation of DNA replication	IBA	J:265628
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	IMP	J:184809
Biological Process	GO:0010389	regulation of G2/M transition of mitotic cell cycle	IMP	J:184809
Biological Process	GO:0090399	replicative senescence	IMP	J:184809
Biological Process	GO:0048536	spleen development	IMP	J:184809
Biological Process	GO:0000723	telomere maintenance	ISO	J:164563
Biological Process	GO:0010833	telomere maintenance via telomere lengthening	IBA	J:265628
Biological Process	GO:0010833	telomere maintenance via telomere lengthening	IMP	J:184809
Biological Process	GO:0048538	thymus development	IMP	J:184809