GO Annotations Graph

• Symbol: Kat8
• Name: K(lysine) acetyltransferase 8
• ID: MGI:1915023

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016407	acetyltransferase activity	IDA	J:150958
Molecular Function	GO:0016746	acyltransferase activity	IEA	J:60000
Molecular Function	GO:0019899	enzyme binding	IPI	J:150958
Molecular Function	GO:0004402	histone acetyltransferase activity	IEA	J:72247
Molecular Function	GO:0004402	histone acetyltransferase activity	IEA	J:72245
Molecular Function	GO:0046972	histone H4K16 acetyltransferase activity	IMP	J:297798
Molecular Function	GO:0046972	histone H4K16 acetyltransferase activity	ISO	J:164563
Molecular Function	GO:0046972	histone H4K16 acetyltransferase activity	ISO	J:164563
Molecular Function	GO:0043995	histone H4K5 acetyltransferase activity	ISO	J:164563
Molecular Function	GO:0043996	histone H4K8 acetyltransferase activity	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:120330
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0003713	transcription coactivator activity	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000123	histone acetyltransferase complex	ISO	J:164563
Cellular Component	GO:0000776	kinetochore	IDA	J:86777
Cellular Component	GO:0071339	MLL1 complex	ISO	J:164563
Cellular Component	GO:0072487	MSL complex	ISO	J:164563
Cellular Component	GO:0044545	NSL complex	ISO	J:164563
Cellular Component	GO:0016363	nuclear matrix	IDA	J:174530
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0016573	histone acetylation	IEA	J:72247
Biological Process	GO:0043984	histone H4-K16 acetylation	ISO	J:164563
Biological Process	GO:0043981	histone H4-K5 acetylation	ISO	J:164563
Biological Process	GO:0043982	histone H4-K8 acetylation	ISO	J:164563
Biological Process	GO:0030099	myeloid cell differentiation	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0022008	neurogenesis	IMP	J:297798
Biological Process	GO:0022008	neurogenesis	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:313850
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	NAS	J:313850
Biological Process	GO:0051571	positive regulation of histone H3-K4 methylation	ISO	J:164563
Biological Process	GO:0010506	regulation of autophagy	ISO	J:73065
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:1900095	regulation of dosage compensation by inactivation of X chromosome	IDA	J:313850