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GO Annotations Graph
Symbol
Name
ID
Kcne2
potassium voltage-gated channel, Isk-related subfamily, gene 2
MGI:1891123

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005251contributes_to
delayed rectifier potassium channel activity
ISOJ:164563
Molecular FunctionGO:0005251contributes_to
delayed rectifier potassium channel activity
ISOJ:155856
Molecular FunctionGO:0005242contributes_to
inward rectifier potassium channel activity
ISOJ:164563
Molecular FunctionGO:0005242contributes_to
inward rectifier potassium channel activity
ISOJ:155856
Molecular FunctionGO:0044325ion channel bindingISOJ:164563
Molecular FunctionGO:0044325ion channel bindingISOJ:155856
Molecular FunctionGO:0005267potassium channel activityIEAJ:60000
Molecular FunctionGO:0015459potassium channel regulator activityISOJ:164563
Molecular FunctionGO:0015459potassium channel regulator activityISOJ:155856
Molecular FunctionGO:0005515protein bindingIPIJ:140247
Molecular FunctionGO:0005515protein bindingIPIJ:140247
Molecular FunctionGO:0042803protein homodimerization activityISOJ:155856
Molecular FunctionGO:0005244voltage-gated ion channel activityIEAJ:60000
Molecular FunctionGO:0005249voltage-gated potassium channel activityISOJ:155856
Molecular FunctionGO:1902282voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarizationISOJ:164563
Cellular ComponentGO:0009986cell surfaceISOJ:164563
Cellular ComponentGO:0016021integral component of membraneISOJ:155856
Cellular ComponentGO:0005764lysosomeISOJ:164563
Cellular ComponentGO:0016020membraneIDAJ:140247
Cellular ComponentGO:0005886plasma membraneISOJ:164563
Cellular ComponentGO:0005886plasma membraneISOJ:155856
Cellular ComponentGO:0008076voltage-gated potassium channel complexISOJ:155856
Cellular ComponentGO:0008076colocalizes_with
voltage-gated potassium channel complex
ISOJ:164563
Cellular ComponentGO:0008076colocalizes_with
voltage-gated potassium channel complex
ISOJ:155856
Cellular ComponentGO:0008076voltage-gated potassium channel complexISOJ:164563
Biological ProcessGO:0086002cardiac muscle cell action potential involved in contractionISOJ:164563
Biological ProcessGO:0034613cellular protein localizationIMPJ:140247
Biological ProcessGO:0035690cellular response to drugISOJ:164563
Biological ProcessGO:0035690cellular response to drugISOJ:155856
Biological ProcessGO:0006811ion transportIEAJ:60000
Biological ProcessGO:0006811ion transportIEAJ:72247
Biological ProcessGO:0086009membrane repolarizationISOJ:164563
Biological ProcessGO:0086009membrane repolarizationISOJ:155856
Biological ProcessGO:0086011membrane repolarization during action potentialISOJ:155856
Biological ProcessGO:0086011membrane repolarization during action potentialISOJ:164563
Biological ProcessGO:1902260negative regulation of delayed rectifier potassium channel activityISOJ:164563
Biological ProcessGO:1902260negative regulation of delayed rectifier potassium channel activityISOJ:155856
Biological ProcessGO:1903817negative regulation of voltage-gated potassium channel activityISOJ:155856
Biological ProcessGO:1901800positive regulation of proteasomal protein catabolic processISOJ:164563
Biological ProcessGO:1901387positive regulation of voltage-gated calcium channel activityISOJ:155856
Biological ProcessGO:0071435potassium ion exportISOJ:155856
Biological ProcessGO:0071435potassium ion exportISOJ:164563
Biological ProcessGO:0010107potassium ion importISOJ:164563
Biological ProcessGO:0010107potassium ion importISOJ:155856
Biological ProcessGO:0071805potassium ion transmembrane transportISOJ:155856
Biological ProcessGO:0071805potassium ion transmembrane transportIMPJ:140247
Biological ProcessGO:0071805potassium ion transmembrane transportISOJ:164563
Biological ProcessGO:0006813potassium ion transportIEAJ:60000
Biological ProcessGO:0006813potassium ion transportIEAJ:72247
Biological ProcessGO:1902159regulation of cyclic nucleotide-gated ion channel activityISOJ:155856
Biological ProcessGO:1902259regulation of delayed rectifier potassium channel activityISOJ:164563
Biological ProcessGO:1902259regulation of delayed rectifier potassium channel activityISOJ:155856
Biological ProcessGO:0086091regulation of heart rate by cardiac conductionISOJ:164563
Biological ProcessGO:1901979regulation of inward rectifier potassium channel activityISOJ:155856
Biological ProcessGO:1901979regulation of inward rectifier potassium channel activityISOJ:164563
Biological ProcessGO:0034765regulation of ion transmembrane transportIEAJ:60000
Biological ProcessGO:0060306regulation of membrane repolarizationISOJ:155856
Biological ProcessGO:0060306regulation of membrane repolarizationISOJ:164563
Biological ProcessGO:1901379regulation of potassium ion transmembrane transportISOJ:155856
Biological ProcessGO:1901379regulation of potassium ion transmembrane transportISOJ:164563
Biological ProcessGO:0060307regulation of ventricular cardiac muscle cell membrane repolarizationIMPJ:140247
Biological ProcessGO:0060307regulation of ventricular cardiac muscle cell membrane repolarizationISOJ:164563
Biological ProcessGO:0006810transportIEAJ:60000
Biological ProcessGO:0086005ventricular cardiac muscle cell action potentialISOJ:164563
Biological ProcessGO:0086005ventricular cardiac muscle cell action potentialIMPJ:140247


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2022
MGI 6.20
The Jackson Laboratory