GO Annotations Graph

• Symbol: Mkln1
• Name: muskelin 1, intracellular mediator containing kelch motifs
• ID: MGI:1351638

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IPI	J:247418
Molecular Function	GO:0005515	protein binding	IPI	J:138977
Molecular Function	GO:0005515	protein binding	IPI	J:172591
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:155856
Cellular Component	GO:0005938	cell cortex	IDA	J:59277
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:172591
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	IDA	J:138977
Cellular Component	GO:0005829	cytosol	IDA	J:59277
Cellular Component	GO:0005654	nucleoplasm	IDA	J:138977
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0001726	ruffle	IDA	J:59277
Cellular Component	GO:0045202	synapse	IEA	J:60000
Cellular Component	GO:0000151	ubiquitin ligase complex	ISO	J:164563
Biological Process	GO:0031532	actin cytoskeleton reorganization	IMP	J:138977
Biological Process	GO:0031532	actin cytoskeleton reorganization	IMP	J:59277
Biological Process	GO:0007160	cell-matrix adhesion	IMP	J:59277
Biological Process	GO:0008360	regulation of cell shape	IMP	J:59277
Biological Process	GO:0008360	regulation of cell shape	IMP	J:138977
Biological Process	GO:0002090	regulation of receptor internalization	ISO	J:155856