About   Help   FAQ
GO Annotations Graph
Symbol
Name
ID
Map4k2
mitogen-activated protein kinase kinase kinase kinase 2
MGI:1346883

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005524ATP bindingISOJ:164563
Molecular FunctionGO:0016301kinase activityIEAJ:60000
Molecular FunctionGO:0008349MAP kinase kinase kinase kinase activityIEAJ:72247
Molecular FunctionGO:0031435mitogen-activated protein kinase kinase kinase bindingISOJ:164563
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0004672protein kinase activityIEAJ:72247
Molecular FunctionGO:0004674protein serine/threonine kinase activityIBAJ:161428
Molecular FunctionGO:0004674protein serine/threonine kinase activityISOJ:164563
Molecular FunctionGO:0016740transferase activityIEAJ:60000
Cellular ComponentGO:0005737cytoplasmIBAJ:161428
Cellular ComponentGO:0005794Golgi apparatusIEAJ:60000
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0005886plasma membraneIEAJ:60000
Biological ProcessGO:0007257activation of JUN kinase activityISOJ:164563
Biological ProcessGO:0032147activation of protein kinase activityIBAJ:161428
Biological ProcessGO:0002376immune system processIEAJ:60000
Biological ProcessGO:0045087innate immune responseIEAJ:60000
Biological ProcessGO:0035556intracellular signal transductionISOJ:164563
Biological ProcessGO:0016310phosphorylationIEAJ:60000
Biological ProcessGO:0046330positive regulation of JNK cascadeISOJ:164563
Biological ProcessGO:0006468protein phosphorylationISOJ:164563
Biological ProcessGO:0042981regulation of apoptotic processIBAJ:161428
Biological ProcessGO:0007346regulation of mitotic cell cycleIBAJ:161428
Biological ProcessGO:0023014signal transduction by protein phosphorylationIBAJ:161428
Biological ProcessGO:0031098stress-activated protein kinase signaling cascadeIBAJ:161428
Biological ProcessGO:0006903vesicle targetingIDAJ:36261


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
01/14/2020
MGI 6.14
The Jackson Laboratory