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GO Annotations Graph
Symbol
Name
ID
Map3k2
mitogen-activated protein kinase kinase kinase 2
MGI:1346873

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005524ATP bindingIEAJ:60000
Molecular FunctionGO:0005524ATP bindingIEAJ:72247
Molecular FunctionGO:0016301kinase activityIEAJ:60000
Molecular FunctionGO:0004709MAP kinase kinase kinase activityISOJ:155856
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0005515protein bindingIPIJ:85661
Molecular FunctionGO:0004672protein kinase activityISAJ:89527
Molecular FunctionGO:0019901protein kinase bindingISOJ:164563
Molecular FunctionGO:0004674protein serine/threonine kinase activityIBAJ:161428
Molecular FunctionGO:0016740transferase activityIEAJ:60000
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0005737cytoplasmIBAJ:161428
Cellular ComponentGO:0005829cytosolISOJ:155856
Cellular ComponentGO:0005654nucleoplasmISOJ:164563
Cellular ComponentGO:0005634nucleusISOJ:155856
Biological ProcessGO:0000186activation of MAPKK activityISOJ:155856
Biological ProcessGO:0032147activation of protein kinase activityIBAJ:161428
Biological ProcessGO:0000165MAPK cascadeISOJ:155856
Biological ProcessGO:0016310phosphorylationIEAJ:60000
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedISOJ:164563
Biological ProcessGO:0006468protein phosphorylationISOJ:155856
Biological ProcessGO:0042981regulation of apoptotic processIBAJ:161428
Biological ProcessGO:0007346regulation of mitotic cell cycleIBAJ:161428
Biological ProcessGO:0023014signal transduction by protein phosphorylationIBAJ:161428
Biological ProcessGO:0031098stress-activated protein kinase signaling cascadeIBAJ:161428


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory