GO Annotations Graph

• Symbol: Epn1
• Name: epsin 1
• ID: MGI:1333763

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0035615	clathrin adaptor activity	ISO	J:155856
Molecular Function	GO:0030276	clathrin binding	IBA	J:265628
Molecular Function	GO:0008289	lipid binding	IEA	J:60000
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:155856
Molecular Function	GO:0140313	molecular sequestering activity	ISO	J:164563
Molecular Function	GO:0005543	phospholipid binding	IBA	J:265628
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:155856
Cellular Component	GO:0030125	clathrin vesicle coat	IBA	J:265628
Cellular Component	GO:0005905	clathrin-coated pit	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005768	endosome	IBA	J:265628
Cellular Component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	ISO	J:155856
Cellular Component	GO:0098890	extrinsic component of postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0098888	extrinsic component of presynaptic membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0098794	postsynapse	ISO	J:155856
Cellular Component	GO:0098794	postsynapse	ISO	J:155856
Cellular Component	GO:0098793	presynapse	ISO	J:155856
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	ISO	J:155856
Biological Process	GO:0048568	embryonic organ development	IGI	J:151951
Biological Process	GO:0006897	endocytosis	ISO	J:155856
Biological Process	GO:0006897	endocytosis	IBA	J:265628
Biological Process	GO:0007565	female pregnancy	IGI	J:151951
Biological Process	GO:0001701	in utero embryonic development	IGI	J:151951
Biological Process	GO:0090148	membrane fission	ISO	J:155856
Biological Process	GO:1903671	negative regulation of sprouting angiogenesis	ISO	J:164563
Biological Process	GO:0007219	Notch signaling pathway	IGI	J:151951
Biological Process	GO:1905445	positive regulation of clathrin coat assembly	ISO	J:155856