Robo1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Robo1
roundabout guidance receptor 1
MGI:1274781

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008046	axon guidance receptor activity	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0030275	LRR domain binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:156034
Molecular Function	GO:0005515	protein binding	IPI	J:153134
Cellular Component	GO:0030673	axolemma	IDA	J:89438
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-8985822
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-8985829
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9010235
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9010950
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9011080
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9014847
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:0035904	aorta development	IGI	J:244269
Biological Process	GO:0003180	aortic valve morphogenesis	IGI	J:244269
Biological Process	GO:0007411	axon guidance	ISO	J:155856
Biological Process	GO:0007411	axon guidance	IMP	J:89780
Biological Process	GO:0007411	axon guidance	IMP	J:89438
Biological Process	GO:0016199	axon midline choice point recognition	IGI	J:143208
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0002042	cell migration involved in sprouting angiogenesis	ISO	J:164563
Biological Process	GO:0021836	chemorepulsion involved in postnatal olfactory bulb interneuron migration	ISO	J:164563
Biological Process	GO:0006935	chemotaxis	IEA	J:60000
Biological Process	GO:0060976	coronary vasculature development	IMP	J:222159
Biological Process	GO:0003272	endocardial cushion formation	IGI	J:244269
Biological Process	GO:0007507	heart development	IMP	J:222159
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	ISO	J:164563
Biological Process	GO:0001822	kidney development	IMP	J:231949
Biological Process	GO:0060763	mammary duct terminal end bud growth	IMP	J:106011
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0030336	negative regulation of cell migration	ISO	J:164563
Biological Process	GO:0008285	negative regulation of cell population proliferation	IMP	J:141875
Biological Process	GO:0070100	negative regulation of chemokine-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0010629	negative regulation of gene expression	IDA	J:244269
Biological Process	GO:0033600	negative regulation of mammary gland epithelial cell proliferation	ISO	J:164563
Biological Process	GO:0050925	negative regulation of negative chemotaxis	ISO	J:164563
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0021891	olfactory bulb interneuron development	IGI	J:119469
Biological Process	GO:0003148	outflow tract septum morphogenesis	IGI	J:244269
Biological Process	GO:0050772	positive regulation of axonogenesis	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:244269
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:244269
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:244269
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:244269
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:244269
Biological Process	GO:0043406	positive regulation of MAP kinase activity	ISO	J:164563
Biological Process	GO:0035481	positive regulation of Notch signaling pathway involved in heart induction	IDA	J:244269
Biological Process	GO:0035025	positive regulation of Rho protein signal transduction	ISO	J:164563
Biological Process	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway	ISO	J:164563
Biological Process	GO:0003184	pulmonary valve morphogenesis	IGI	J:244269
Biological Process	GO:0048814	regulation of dendrite morphogenesis	ISO	J:155856
Biological Process	GO:0035385	Roundabout signaling pathway	ISO	J:164563
Biological Process	GO:0003281	ventricular septum development	IMP	J:222159
Biological Process	GO:0060412	ventricular septum morphogenesis	IGI	J:244269

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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