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GO Annotations Graph
Symbol
Name
ID
Tert
telomerase reverse transcriptase
MGI:1202709

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0003677DNA bindingISOJ:164563
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0016779nucleotidyltransferase activityISOJ:164563
Molecular FunctionGO:0005515protein bindingIPIJ:72504
Molecular FunctionGO:0005515protein bindingIPIJ:118302
Molecular FunctionGO:0005515protein bindingIPIJ:217943
Molecular FunctionGO:0042803protein homodimerization activityISOJ:164563
Molecular FunctionGO:0003723RNA bindingISOJ:164563
Molecular FunctionGO:0003964RNA-directed DNA polymerase activityISOJ:164563
Molecular FunctionGO:0003968contributes_to
RNA-directed RNA polymerase activity
ISOJ:164563
Molecular FunctionGO:0003720telomerase activityISOJ:164563
Molecular FunctionGO:0003720telomerase activityIDAJ:87581
Molecular FunctionGO:0003720contributes_to
telomerase activity
ISOJ:164563
Molecular FunctionGO:0070034telomerase RNA bindingIPIJ:227389
Molecular FunctionGO:0070034telomerase RNA bindingIBAJ:161428
Molecular FunctionGO:0070034telomerase RNA bindingISOJ:164563
Molecular FunctionGO:0003721telomerase RNA reverse transcriptase activityISOJ:164563
Molecular FunctionGO:0003721telomerase RNA reverse transcriptase activityIBAJ:161428
Molecular FunctionGO:0003721contributes_to
telomerase RNA reverse transcriptase activity
ISOJ:164563
Molecular FunctionGO:0042162telomeric DNA bindingIBAJ:161428
Molecular FunctionGO:0001223transcription coactivator bindingIPIJ:150343
Molecular FunctionGO:0001223transcription coactivator bindingISOJ:164563
Molecular FunctionGO:0016740transferase activityIEAJ:60000
Molecular FunctionGO:0000049tRNA bindingISOJ:164563
Cellular ComponentGO:0005694chromosomeIEAJ:60000
Cellular ComponentGO:0000781chromosome, telomeric regionIEAJ:60000
Cellular ComponentGO:0005737cytoplasmISOJ:155856
Cellular ComponentGO:0005737cytoplasmIDAJ:217943
Cellular ComponentGO:0030529intracellular ribonucleoprotein complexIEAJ:60000
Cellular ComponentGO:0042645mitochondrial nucleoidISOJ:164563
Cellular ComponentGO:0005739mitochondrionISOJ:155856
Cellular ComponentGO:0005739mitochondrionIDAJ:215869
Cellular ComponentGO:0000784nuclear chromosome, telomeric regionISOJ:164563
Cellular ComponentGO:0005730nucleolusISOJ:164563
Cellular ComponentGO:0005654nucleoplasmISOJ:164563
Cellular ComponentGO:0005634nucleusISOJ:155856
Cellular ComponentGO:0005634nucleusISOJ:164563
Cellular ComponentGO:0005886plasma membraneIDAJ:217943
Cellular ComponentGO:0016605colocalizes_with
PML body
ISOJ:164563
Cellular ComponentGO:0031379RNA-directed RNA polymerase complexISOJ:164563
Cellular ComponentGO:0000333telomerase catalytic core complexIMPJ:100470
Cellular ComponentGO:0000333telomerase catalytic core complexISOJ:164563
Cellular ComponentGO:0005697telomerase holoenzyme complexISOJ:164563
Cellular ComponentGO:1990572TERT-RMRP complexISOJ:164563
Biological ProcessGO:0071456cellular response to hypoxiaISOJ:164563
Biological ProcessGO:0071897DNA biosynthetic processISOJ:164563
Biological ProcessGO:0022616DNA strand elongationISOJ:164563
Biological ProcessGO:0070200establishment of protein localization to telomereISOJ:164563
Biological ProcessGO:0007005mitochondrion organizationISOJ:164563
Biological ProcessGO:0043066negative regulation of apoptotic processISOJ:155856
Biological ProcessGO:2000773negative regulation of cellular senescenceISOJ:164563
Biological ProcessGO:2001240negative regulation of extrinsic apoptotic signaling pathway in absence of ligandISOJ:164563
Biological ProcessGO:0010629negative regulation of gene expressionISOJ:164563
Biological ProcessGO:0060253negative regulation of glial cell proliferationISOJ:155856
Biological ProcessGO:0043524negative regulation of neuron apoptotic processISOJ:155856
Biological ProcessGO:1903704negative regulation of production of siRNA involved in RNA interferenceISOJ:164563
Biological ProcessGO:1900087positive regulation of G1/S transition of mitotic cell cycleISOJ:155856
Biological ProcessGO:0046326positive regulation of glucose importIMPJ:217943
Biological ProcessGO:0042635positive regulation of hair cycleIMPJ:100470
Biological ProcessGO:0042635positive regulation of hair cycleIMPJ:100644
Biological ProcessGO:0051000positive regulation of nitric-oxide synthase activityISOJ:164563
Biological ProcessGO:1902895positive regulation of pri-miRNA transcription from RNA polymerase II promoterISOJ:164563
Biological ProcessGO:0032092positive regulation of protein bindingISOJ:164563
Biological ProcessGO:1904751positive regulation of protein localization to nucleolusISOJ:164563
Biological ProcessGO:2000648positive regulation of stem cell proliferationIMPJ:100644
Biological ProcessGO:2000648positive regulation of stem cell proliferationIMPJ:100470
Biological ProcessGO:1903620positive regulation of transdifferentiationISOJ:155856
Biological ProcessGO:1904754positive regulation of vascular associated smooth muscle cell migrationISOJ:155856
Biological ProcessGO:1904707positive regulation of vascular smooth muscle cell proliferationISOJ:155856
Biological ProcessGO:0030177positive regulation of Wnt signaling pathwayISOJ:164563
Biological ProcessGO:0030177positive regulation of Wnt signaling pathwayIGIJ:150343
Biological ProcessGO:0030422production of siRNA involved in RNA interferenceISOJ:164563
Biological ProcessGO:1904173regulation of histone demethylase activity (H3-K4 specific)TASJ:185349
Biological ProcessGO:0031647regulation of protein stabilityISOJ:164563
Biological ProcessGO:0090399replicative senescenceISOJ:164563
Biological ProcessGO:0032774RNA biosynthetic processISOJ:164563
Biological ProcessGO:0006278RNA-dependent DNA replicationISOJ:164563
Biological ProcessGO:0007004telomere maintenance via telomeraseIBAJ:161428
Biological ProcessGO:0007004telomere maintenance via telomeraseISOJ:164563
Biological ProcessGO:0001172transcription, RNA-templatedISOJ:164563


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory