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GO Annotations Graph
Symbol
Name
ID
Bub1
BUB1, mitotic checkpoint serine/threonine kinase
MGI:1100510

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005524ATP bindingIEAJ:72247
Molecular FunctionGO:0005524ATP bindingIEAJ:60000
Molecular FunctionGO:0016301kinase activityIEAJ:60000
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0004672protein kinase activityIEAJ:72247
Molecular FunctionGO:0004674protein serine/threonine kinase activityIEAJ:60000
Molecular FunctionGO:0016740transferase activityIEAJ:60000
Cellular ComponentGO:0005694chromosomeIEAJ:60000
Cellular ComponentGO:0000775chromosome, centromeric regionIDAJ:80450
Cellular ComponentGO:0000777condensed chromosome kinetochoreISOJ:164563
Cellular ComponentGO:0000942condensed nuclear chromosome outer kinetochoreISOJ:164563
Cellular ComponentGO:0000780condensed nuclear chromosome, centromeric regionIDAJ:130184
Cellular ComponentGO:0000780condensed nuclear chromosome, centromeric regionIDAJ:155745
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0000776kinetochoreISOJ:73065
Cellular ComponentGO:0000776kinetochoreIDAJ:119076
Cellular ComponentGO:0000776kinetochoreIDAJ:135093
Cellular ComponentGO:0000776kinetochoreISOJ:73065
Cellular ComponentGO:0000776kinetochoreIDAJ:91435
Cellular ComponentGO:0016020membraneISOJ:164563
Cellular ComponentGO:0005654nucleoplasmISOJ:164563
Cellular ComponentGO:0005634nucleusIEAJ:60000
Biological ProcessGO:0006915apoptotic processIEAJ:60000
Biological ProcessGO:0007049cell cycleIEAJ:60000
Biological ProcessGO:0051301cell divisionIEAJ:60000
Biological ProcessGO:0007059chromosome segregationIMPJ:135093
Biological ProcessGO:0009790embryo developmentIDAJ:159053
Biological ProcessGO:0007067mitotic nuclear divisionIEAJ:60000
Biological ProcessGO:0007094mitotic spindle assembly checkpointIEAJ:72247
Biological ProcessGO:0071174mitotic spindle checkpointIMPJ:135093
Biological ProcessGO:0016310phosphorylationIEAJ:60000
Biological ProcessGO:2001244positive regulation of intrinsic apoptotic signaling pathwayIMPJ:135093
Biological ProcessGO:0006468protein phosphorylationIEAJ:72247
Biological ProcessGO:0051983regulation of chromosome segregationISOJ:164563
Biological ProcessGO:0007063regulation of sister chromatid cohesionISOJ:164563
Biological ProcessGO:0071173spindle assembly checkpointISOJ:164563
Biological ProcessGO:0071173spindle assembly checkpointIDAJ:128455


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory