GO Annotations Graph

• Symbol: Terf1
• Name: telomeric repeat binding factor 1
• ID: MGI:109634

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0071532	ankyrin repeat binding	ISO	J:164563
Molecular Function	GO:0071532	ankyrin repeat binding	IBA	J:265628
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0008301	DNA binding, bending	ISO	J:164563
Molecular Function	GO:0008301	DNA binding, bending	IBA	J:265628
Molecular Function	GO:0003691	double-stranded telomeric DNA binding	ISO	J:164563
Molecular Function	GO:0003691	double-stranded telomeric DNA binding	ISO	J:164563
Molecular Function	GO:0003691	double-stranded telomeric DNA binding	IBA	J:265628
Molecular Function	GO:0098505	G-rich strand telomeric DNA binding	ISO	J:164563
Molecular Function	GO:0098505	G-rich strand telomeric DNA binding	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0008017	microtubule binding	ISO	J:164563
Molecular Function	GO:0008017	microtubule binding	IBA	J:265628
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:205574
Molecular Function	GO:0005515	protein binding	IPI	J:198831
Molecular Function	GO:0005515	protein binding	IPI	J:205574
Molecular Function	GO:0005515	protein binding	IPI	J:82975
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0003720	telomerase activity	ISO	J:164563
Molecular Function	GO:0003720	telomerase activity	IBA	J:265628
Molecular Function	GO:0042162	telomeric DNA binding	ISO	J:164563
Molecular Function	GO:0042162	telomeric DNA binding	IDA	J:159049
Molecular Function	GO:0042162	telomeric DNA binding	ISO	J:164563
Molecular Function	GO:0042162	telomeric DNA binding	IDA	J:199000
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000781	chromosome, telomeric region	ISO	J:164563
Cellular Component	GO:0000781	chromosome, telomeric region	IDA	J:228117
Cellular Component	GO:0000781	chromosome, telomeric region	ISO	J:164563
Cellular Component	GO:0000781	chromosome, telomeric region	IDA	J:199000
Cellular Component	GO:0000781	chromosome, telomeric region	IDA	J:115639
Cellular Component	GO:0000781	chromosome, telomeric region	IDA	J:270644
Cellular Component	GO:0000781	chromosome, telomeric region	IDA	J:209347
Cellular Component	GO:0000781	chromosome, telomeric region	IDA	J:105516
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0001650	fibrillar center	ISO	J:164563
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0000783	nuclear telomere cap complex	ISO	J:164563
Cellular Component	GO:0000783	nuclear telomere cap complex	IDA	J:30144
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-912355
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:131948
Cellular Component	GO:0070187	shelterin complex	ISO	J:164563
Cellular Component	GO:0005819	spindle	ISO	J:164563
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0000237	leptotene	IMP	J:147391
Biological Process	GO:0045141	meiotic telomere clustering	IMP	J:147391
Biological Process	GO:0008156	negative regulation of DNA replication	ISO	J:164563
Biological Process	GO:0008156	negative regulation of DNA replication	IBA	J:265628
Biological Process	GO:1904850	negative regulation of establishment of protein localization to telomere	ISO	J:164563
Biological Process	GO:1904911	negative regulation of establishment of RNA localization to telomere	ISO	J:164563
Biological Process	GO:1905778	negative regulation of exonuclease activity	ISO	J:164563
Biological Process	GO:1905778	negative regulation of exonuclease activity	IBA	J:265628
Biological Process	GO:0051974	negative regulation of telomerase activity	ISO	J:164563
Biological Process	GO:0032211	negative regulation of telomere maintenance via telomerase	ISO	J:164563
Biological Process	GO:1905839	negative regulation of telomeric D-loop disassembly	ISO	J:164563
Biological Process	GO:1905839	negative regulation of telomeric D-loop disassembly	IBA	J:265628
Biological Process	GO:1904792	positive regulation of shelterin complex assembly	ISO	J:164563
Biological Process	GO:0032206	positive regulation of telomere maintenance	NAS	J:319993
Biological Process	GO:0016233	telomere capping	ISO	J:164563
Biological Process	GO:0000723	telomere maintenance	ISO	J:164563
Biological Process	GO:0007004	telomere maintenance via telomerase	ISO	J:164563
Biological Process	GO:0007004	telomere maintenance via telomerase	ISO	J:164563
Biological Process	GO:0007004	telomere maintenance via telomerase	IBA	J:265628
Biological Process	GO:0061820	telomeric D-loop disassembly	ISO	J:164563