GO Annotations Graph

• Symbol: Tia1
• Name: cytotoxic granule-associated RNA binding protein 1
• ID: MGI:107914

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0035925	mRNA 3'-UTR AU-rich region binding	IDA	J:88770
Molecular Function	GO:0003730	mRNA 3'-UTR binding	IDA	J:314555
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:175158
Molecular Function	GO:0003723	RNA binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:314554
Cellular Component	GO:0005737	cytoplasm	IDA	J:82058
Cellular Component	GO:0010494	cytoplasmic stress granule	IDA	J:314553
Cellular Component	GO:0010494	cytoplasmic stress granule	ISO	J:155856
Cellular Component	GO:0010494	cytoplasmic stress granule	ISO	J:164563
Cellular Component	GO:0010494	cytoplasmic stress granule	IDA	J:259116
Cellular Component	GO:0010494	cytoplasmic stress granule	IDA	J:179583
Cellular Component	GO:0010494	cytoplasmic stress granule	IDA	J:177884
Cellular Component	GO:0010494	cytoplasmic stress granule	ISO	J:197742
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0097165	nuclear stress granule	IDA	J:179583
Cellular Component	GO:0097165	nuclear stress granule	ISO	J:197742
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:82058
Cellular Component	GO:0005634	nucleus	IDA	J:112748
Cellular Component	GO:1990904	ribonucleoprotein complex	ISO	J:155856
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0006397	mRNA processing	IEA	J:60000
Biological Process	GO:0001818	negative regulation of cytokine production	IMP	J:88770
Biological Process	GO:0017148	negative regulation of translation	IDA	J:314555
Biological Process	GO:0017148	negative regulation of translation	IMP	J:88770
Biological Process	GO:1904037	positive regulation of epithelial cell apoptotic process	ISO	J:155856
Biological Process	GO:1903608	protein localization to cytoplasmic stress granule	ISO	J:164563
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	ISO	J:164563
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	IDA	J:314640
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	IDA	J:314554
Biological Process	GO:0048024	regulation of mRNA splicing, via spliceosome	ISO	J:164563
Biological Process	GO:0008380	RNA splicing	IEA	J:60000
Biological Process	GO:0034063	stress granule assembly	ISO	J:164563