GO Annotations Graph

• Symbol: Sin3a
• Name: transcriptional regulator, SIN3A (yeast)
• ID: MGI:107157

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:136812
Molecular Function	GO:0003682	chromatin binding	IDA	J:117710
Molecular Function	GO:0003677	DNA binding	IDA	J:86311
Molecular Function	GO:0003677	DNA binding	IDA	J:99406
Molecular Function	GO:0005515	protein binding	IPI	J:243422
Molecular Function	GO:0005515	protein binding	IPI	J:171270
Molecular Function	GO:0005515	protein binding	IPI	J:203745
Molecular Function	GO:0005515	protein binding	IPI	J:150926
Molecular Function	GO:0005515	protein binding	IPI	J:206161
Molecular Function	GO:0005515	protein binding	IPI	J:66985
Molecular Function	GO:0005515	protein binding	IPI	J:84768
Molecular Function	GO:0005515	protein binding	IPI	J:161034
Molecular Function	GO:0005515	protein binding	IPI	J:148391
Molecular Function	GO:0005515	protein binding	IPI	J:61357
Molecular Function	GO:0005515	protein binding	IPI	J:118818
Molecular Function	GO:0005515	protein binding	IPI	J:160317
Molecular Function	GO:0005515	protein binding	IPI	J:175112
Molecular Function	GO:0005515	protein binding	IPI	J:306579
Molecular Function	GO:0005515	protein binding	IPI	J:169899
Molecular Function	GO:0005515	protein binding	IPI	J:172063
Molecular Function	GO:0005515	protein binding	IPI	J:144189
Molecular Function	GO:0005515	protein binding	IPI	J:31975
Molecular Function	GO:0005515	protein binding	IPI	J:227377
Molecular Function	GO:0005515	protein binding	IPI	J:148368
Molecular Function	GO:0005515	protein binding	IPI	J:173532
Molecular Function	GO:0005515	protein binding	IPI	J:217746
Molecular Function	GO:0005515	protein binding	IPI	J:159082
Molecular Function	GO:0005515	protein binding	IPI	J:102172
Molecular Function	GO:0005515	protein binding	IPI	J:95153
Molecular Function	GO:0005515	protein binding	IPI	J:159082
Molecular Function	GO:0005515	protein binding	IPI	J:159082
Molecular Function	GO:0005515	protein binding	IPI	J:64684
Molecular Function	GO:0005515	protein binding	IPI	J:32479
Molecular Function	GO:0005515	protein binding	IPI	J:81403
Molecular Function	GO:0005515	protein binding	IPI	J:104074
Molecular Function	GO:0005515	protein binding	IPI	J:105563
Molecular Function	GO:0005515	protein binding	IPI	J:66140
Molecular Function	GO:0005515	protein binding	IPI	J:102172
Molecular Function	GO:0005515	protein binding	IPI	J:126723
Molecular Function	GO:0005515	protein binding	IPI	J:29949
Molecular Function	GO:0005515	protein binding	IPI	J:29949
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0003723	RNA binding	ISO	J:155856
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	IPI	J:146223
Molecular Function	GO:0003713	transcription coactivator activity	ISO	J:164563
Molecular Function	GO:0003714	transcription corepressor activity	ISO	J:164563
Molecular Function	GO:0003714	transcription corepressor activity	IDA	J:61357
Molecular Function	GO:0003714	transcription corepressor activity	IGI	J:61357
Molecular Function	GO:0003714	transcription corepressor activity	IDA	J:32479
Molecular Function	GO:0003714	transcription corepressor activity	IBA	J:265628
Molecular Function	GO:0003714	transcription corepressor activity	IMP	J:99406
Molecular Function	GO:0008134	transcription factor binding	IPI	J:97581
Molecular Function	GO:0008134	transcription factor binding	IPI	J:86311
Molecular Function	GO:0140416	transcription regulator inhibitor activity	ISO	J:164563
Cellular Component	GO:0000785	chromatin	ISO	J:155856
Cellular Component	GO:0000785	chromatin	IBA	J:265628
Cellular Component	GO:0000118	histone deacetylase complex	ISO	J:164563
Cellular Component	GO:0000776	kinetochore	IDA	J:86777
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-573336
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-573376
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-573383
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9006133
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9017958
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9625109
Cellular Component	GO:0005634	nucleus	IDA	J:61357
Cellular Component	GO:0005634	nucleus	NAS	J:243422
Cellular Component	GO:0005634	nucleus	IDA	J:31975
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0016580	Sin3 complex	ISO	J:164563
Cellular Component	GO:0016580	Sin3 complex	NAS	J:243422
Cellular Component	GO:0016580	Sin3 complex	IBA	J:265628
Cellular Component	GO:0005667	transcription regulator complex	IPI	J:123890
Cellular Component	GO:0005667	transcription regulator complex	IPI	J:123890
Cellular Component	GO:0005667	transcription regulator complex	IPI	J:123890
Cellular Component	GO:0005667	transcription regulator complex	IPI	J:123890
Cellular Component	GO:0005667	transcription regulator complex	IPI	J:123890
Cellular Component	GO:0017053	transcription repressor complex	IDA	J:61357
Cellular Component	GO:0017053	transcription repressor complex	IPI	J:123890
Cellular Component	GO:0017053	transcription repressor complex	IPI	J:123890
Cellular Component	GO:0017053	transcription repressor complex	IPI	J:123890
Cellular Component	GO:0017053	transcription repressor complex	IPI	J:123890
Cellular Component	GO:0017053	transcription repressor complex	IPI	J:123890
Biological Process	GO:0002218	activation of innate immune response	ISO	J:164563
Biological Process	GO:0007568	aging	ISO	J:155856
Biological Process	GO:0071333	cellular response to glucose stimulus	IDA	J:126723
Biological Process	GO:0021895	cerebral cortex neuron differentiation	IMP	J:281257
Biological Process	GO:0006260	DNA replication	IMP	J:99406
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	IMP	J:202604
Biological Process	GO:0001701	in utero embryonic development	IMP	J:99406
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:99406
Biological Process	GO:0030336	negative regulation of cell migration	NAS	J:320045
Biological Process	GO:0042754	negative regulation of circadian rhythm	IMP	J:173532
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:61357
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:32479
Biological Process	GO:1900181	negative regulation of protein localization to nucleus	ISO	J:164563
Biological Process	GO:1902455	negative regulation of stem cell population maintenance	NAS	J:243422
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	NAS	J:320044
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	NAS	J:320043
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:56497
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:56497
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:82479
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:32479
Biological Process	GO:2000678	negative regulation of transcription regulatory region DNA binding	ISO	J:164563
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	NAS	J:320045
Biological Process	GO:0002230	positive regulation of defense response to virus by host	ISO	J:164563
Biological Process	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	IMP	J:99406
Biological Process	GO:0031453	positive regulation of heterochromatin formation	ISO	J:164563
Biological Process	GO:0045666	positive regulation of neuron differentiation	IMP	J:281257
Biological Process	GO:1902459	positive regulation of stem cell population maintenance	NAS	J:243422
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0006476	protein deacetylation	ISO	J:164563
Biological Process	GO:0008104	protein localization	IMP	J:99406
Biological Process	GO:0030516	regulation of axon extension	IMP	J:281257
Biological Process	GO:0006355	regulation of DNA-templated transcription	IMP	J:99406
Biological Process	GO:0010817	regulation of hormone levels	ISO	J:155856
Biological Process	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	ISO	J:155856
Biological Process	GO:0051595	response to methylglyoxal	IDA	J:126723
Biological Process	GO:0010243	response to organonitrogen compound	ISO	J:155856
Biological Process	GO:0048511	rhythmic process	IEA	J:60000