GO Annotations Graph

• Symbol: Dvl2
• Name: dishevelled segment polarity protein 2
• ID: MGI:106613

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005109	frizzled binding	IPI	J:170222
Molecular Function	GO:0005109	frizzled binding	ISO	J:164563
Molecular Function	GO:0005109	frizzled binding	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	IPI	J:175318
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IPI	J:245311
Molecular Function	GO:0005515	protein binding	IPI	J:175318
Molecular Function	GO:0005515	protein binding	IPI	J:200479
Molecular Function	GO:0005515	protein binding	IPI	J:248270
Molecular Function	GO:0005515	protein binding	IPI	J:152701
Molecular Function	GO:0005515	protein binding	IPI	J:245339
Molecular Function	GO:0005515	protein binding	IPI	J:221860
Molecular Function	GO:0005515	protein binding	IPI	J:192848
Molecular Function	GO:0005515	protein binding	IPI	J:83951
Molecular Function	GO:0005515	protein binding	IPI	J:95171
Molecular Function	GO:0005515	protein binding	IPI	J:170262
Molecular Function	GO:0005515	protein binding	IPI	J:192848
Molecular Function	GO:0005515	protein binding	IPI	J:248207
Molecular Function	GO:0005515	protein binding	IPI	J:227365
Molecular Function	GO:0005515	protein binding	IPI	J:177735
Molecular Function	GO:0005515	protein binding	IPI	J:274568
Molecular Function	GO:0005515	protein binding	IPI	J:187547
Molecular Function	GO:0005515	protein binding	IPI	J:199855
Molecular Function	GO:0005515	protein binding	IPI	J:155567
Molecular Function	GO:0019904	protein domain specific binding	IPI	J:96879
Molecular Function	GO:0019901	protein kinase binding	IPI	J:120773
Molecular Function	GO:0043621	protein self-association	IDA	J:175318
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	IDA	J:192848
Molecular Function	GO:0031267	small GTPase binding	IPI	J:192848
Cellular Component	GO:0016235	aggresome	ISO	J:164563
Cellular Component	GO:0045177	apical part of cell	IDA	J:147041
Cellular Component	GO:0005938	cell cortex	ISO	J:55044
Cellular Component	GO:0030136	clathrin-coated vesicle	IDA	J:132987
Cellular Component	GO:0005737	cytoplasm	IDA	J:120773
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:153468
Cellular Component	GO:0005737	cytoplasm	ISO	J:55044
Cellular Component	GO:0005737	cytoplasm	IDA	J:199623
Cellular Component	GO:0005737	cytoplasm	ISO	J:195239
Cellular Component	GO:0005737	cytoplasm	IDA	J:124214
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:195239
Cellular Component	GO:0005856	cytoskeleton	NAS	J:146735
Cellular Component	GO:0005829	cytosol	IDA	J:192848
Cellular Component	GO:0005829	cytosol	IDA	J:175318
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0016328	lateral plasma membrane	IDA	J:195272
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IMP	J:153468
Cellular Component	GO:0005886	plasma membrane	IDA	J:168261
Cellular Component	GO:0005886	plasma membrane	IDA	J:132987
Cellular Component	GO:0005886	plasma membrane	IGI	J:124214
Cellular Component	GO:0005886	plasma membrane	IDA	J:100861
Cellular Component	GO:0005886	plasma membrane	IDA	J:108512
Biological Process	GO:0060070	canonical Wnt signaling pathway	IMP	J:227385
Biological Process	GO:0060070	canonical Wnt signaling pathway	IMP	J:175318
Biological Process	GO:0060070	canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0060070	canonical Wnt signaling pathway	IBA	J:265628
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:124214
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:140886
Biological Process	GO:0060070	canonical Wnt signaling pathway	IMP	J:142392
Biological Process	GO:0060070	canonical Wnt signaling pathway	IMP	J:142392
Biological Process	GO:0060070	canonical Wnt signaling pathway	IMP	J:142392
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:35543
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:56401
Biological Process	GO:0044340	canonical Wnt signaling pathway involved in regulation of cell proliferation	ISO	J:164563
Biological Process	GO:0090103	cochlea morphogenesis	IGI	J:100861
Biological Process	GO:0090103	cochlea morphogenesis	IGI	J:142392
Biological Process	GO:0022007	convergent extension involved in neural plate elongation	IMP	J:108512
Biological Process	GO:0022007	convergent extension involved in neural plate elongation	IGI	J:108512
Biological Process	GO:0022007	convergent extension involved in neural plate elongation	IGI	J:108512
Biological Process	GO:0060029	convergent extension involved in organogenesis	IGI	J:100861
Biological Process	GO:0007507	heart development	IMP	J:80691
Biological Process	GO:0007507	heart development	IMP	J:79834
Biological Process	GO:0001947	heart looping	IGI	J:188039
Biological Process	GO:0003007	heart morphogenesis	IGI	J:142392
Biological Process	GO:0035556	intracellular signal transduction	IEA	J:72247
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0001843	neural tube closure	IMP	J:79834
Biological Process	GO:0035567	non-canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0003151	outflow tract morphogenesis	IMP	J:80691
Biological Process	GO:0003151	outflow tract morphogenesis	IGI	J:188039
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IBA	J:265628
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IGI	J:108512
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IMP	J:108512
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IGI	J:108512
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	ISO	J:164563
Biological Process	GO:0043547	positive regulation of GTPase activity	IDA	J:192848
Biological Process	GO:0043507	positive regulation of JUN kinase activity	ISO	J:164563
Biological Process	GO:0043507	positive regulation of JUN kinase activity	IDA	J:164791
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:0061098	positive regulation of protein tyrosine kinase activity	IGI	J:155567
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0008104	protein localization	IDA	J:124214
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0007379	segment specification	IMP	J:79834
Biological Process	GO:0035282	segmentation	IGI	J:35543
Biological Process	GO:0016055	Wnt signaling pathway	IMP	J:213772
Biological Process	GO:0060071	Wnt signaling pathway, planar cell polarity pathway	ISO	J:164563
Biological Process	GO:0060071	Wnt signaling pathway, planar cell polarity pathway	IGI	J:100861