GO Annotations Graph

• Symbol: G6pd2
• Name: glucose-6-phosphate dehydrogenase 2
• ID: MGI:105977

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0030246	carbohydrate binding	ISO	J:155856
Molecular Function	GO:0005536	glucose binding	ISO	J:155856
Molecular Function	GO:0005536	glucose binding	ISO	J:164563
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	ISO	J:164563
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	ISO	J:155856
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	IBA	J:265628
Molecular Function	GO:0004345	glucose-6-phosphate dehydrogenase activity	IDA	J:40148
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0050661	NADP binding	ISO	J:155856
Molecular Function	GO:0050661	NADP binding	ISO	J:164563
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	IEA	J:72247
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Cellular Component	GO:0034451	centriolar satellite	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Biological Process	GO:0005975	carbohydrate metabolic process	IEA	J:60000
Biological Process	GO:0034599	cellular response to oxidative stress	ISO	J:164563
Biological Process	GO:0006695	cholesterol biosynthetic process	ISO	J:164563
Biological Process	GO:0043249	erythrocyte maturation	ISO	J:164563
Biological Process	GO:0051156	glucose 6-phosphate metabolic process	ISO	J:155856
Biological Process	GO:0051156	glucose 6-phosphate metabolic process	ISO	J:164563
Biological Process	GO:0006006	glucose metabolic process	IBA	J:265628
Biological Process	GO:0006749	glutathione metabolic process	ISO	J:164563
Biological Process	GO:0006739	NADP metabolic process	ISO	J:164563
Biological Process	GO:0006740	NADPH regeneration	ISO	J:164563
Biological Process	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development	ISO	J:155856
Biological Process	GO:0010734	negative regulation of protein glutathionylation	ISO	J:164563
Biological Process	GO:2000378	negative regulation of reactive oxygen species metabolic process	ISO	J:155856
Biological Process	GO:0019322	pentose biosynthetic process	ISO	J:164563
Biological Process	GO:0006098	pentose-phosphate shunt	ISO	J:155856
Biological Process	GO:0006098	pentose-phosphate shunt	ISO	J:164563
Biological Process	GO:0009051	pentose-phosphate shunt, oxidative branch	ISO	J:164563
Biological Process	GO:0009051	pentose-phosphate shunt, oxidative branch	ISO	J:155856
Biological Process	GO:0009051	pentose-phosphate shunt, oxidative branch	IBA	J:265628
Biological Process	GO:1904879	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	ISO	J:155856
Biological Process	GO:0043523	regulation of neuron apoptotic process	ISO	J:155856
Biological Process	GO:0045471	response to ethanol	ISO	J:155856
Biological Process	GO:0046390	ribose phosphate biosynthetic process	ISO	J:164563