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GO Annotations Graph
Symbol
Name
ID
Lepr
leptin receptor
MGI:104993

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0004896cytokine receptor activityIEAJ:72247
Molecular FunctionGO:0042802identical protein bindingISOJ:164563
Molecular FunctionGO:0038021leptin receptor activityIMPJ:82334
Molecular FunctionGO:0017046peptide hormone bindingISOJ:155856
Molecular FunctionGO:0005515protein bindingIPIJ:109624
Molecular FunctionGO:0005515protein bindingIPIJ:146158
Molecular FunctionGO:0005515protein bindingIPIJ:146158
Molecular FunctionGO:0005515protein bindingIPIJ:146158
Molecular FunctionGO:0016500protein-hormone receptor activityISOJ:155856
Molecular FunctionGO:0004888transmembrane signaling receptor activityTASJ:38955
Cellular ComponentGO:0005576extracellular regionIEAJ:60000
Cellular ComponentGO:0005615extracellular spaceISOJ:155856
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0005887integral component of plasma membraneTASJ:38955
Cellular ComponentGO:0016020membraneIEAJ:72247
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0005886plasma membraneISOJ:155856
Cellular ComponentGO:0043235receptor complexISOJ:194542
Biological ProcessGO:0001525angiogenesisISOJ:155856
Biological ProcessGO:0098868bone growthIMPJ:60001
Biological ProcessGO:0008203cholesterol metabolic processIGIJ:100492
Biological ProcessGO:0042755eating behaviorISOJ:155856
Biological ProcessGO:0097009energy homeostasisIMPJ:82334
Biological ProcessGO:0007186G-protein coupled receptor signaling pathwayISOJ:155856
Biological ProcessGO:0042593glucose homeostasisIMPJ:219525
Biological ProcessGO:0042593glucose homeostasisIMPJ:82334
Biological ProcessGO:0033210leptin-mediated signaling pathwayISOJ:155856
Biological ProcessGO:0033210leptin-mediated signaling pathwayIMPJ:82334
Biological ProcessGO:0010507negative regulation of autophagyISOJ:164563
Biological ProcessGO:1903999negative regulation of eating behaviorISOJ:155856
Biological ProcessGO:0045721negative regulation of gluconeogenesisIMPJ:204007
Biological ProcessGO:0051346negative regulation of hydrolase activityIGIJ:100492
Biological ProcessGO:1904060negative regulation of locomotor rhythmISOJ:155856
Biological ProcessGO:0035774positive regulation of insulin secretion involved in cellular response to glucose stimulusISOJ:155856
Biological ProcessGO:0043410positive regulation of MAPK cascadeISOJ:155856
Biological ProcessGO:0046850regulation of bone remodelingIMPJ:60001
Biological ProcessGO:2000505regulation of energy homeostasisIMPJ:219525
Biological ProcessGO:0060259regulation of feeding behaviorIMPJ:82334
Biological ProcessGO:0019222regulation of metabolic processTASJ:38955
Biological ProcessGO:0044321response to leptinIMPJ:82334
Biological ProcessGO:0019953sexual reproductionIMPJ:82334
Biological ProcessGO:0007165signal transductionTASJ:38955
Biological ProcessGO:0030217T cell differentiationIMPJ:49623


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/12/2021
MGI 6.16
The Jackson Laboratory