GO Annotations Graph

• Symbol: Pou4f2
• Name: POU domain, class 4, transcription factor 2
• ID: MGI:102524

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:134978
Molecular Function	GO:0003682	chromatin binding	IDA	J:134978
Molecular Function	GO:0003682	chromatin binding	IDA	J:134978
Molecular Function	GO:0003682	chromatin binding	IDA	J:134978
Molecular Function	GO:0003682	chromatin binding	IDA	J:164295
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IMP	J:239207
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:139182
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:235989
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:239207
Molecular Function	GO:0003700	DNA-binding transcription factor activity	TAS	J:66507
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISS	J:17714
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IMP	J:182786
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	J:175131
Molecular Function	GO:0002039	p53 binding	IPI	J:239207
Molecular Function	GO:1990841	promoter-specific chromatin binding	IDA	J:239207
Molecular Function	GO:1990841	promoter-specific chromatin binding	IDA	J:239195
Molecular Function	GO:0005515	protein binding	IPI	J:239215
Molecular Function	GO:0005515	protein binding	IPI	J:182786
Molecular Function	GO:0005515	protein binding	IPI	J:239207
Molecular Function	GO:0005515	protein binding	IPI	J:30561
Molecular Function	GO:0005515	protein binding	IPI	J:239195
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:239205
Molecular Function	GO:0043565	sequence-specific DNA binding	IMP	J:16381
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:41168
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:235989
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:239195
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:239217
Cellular Component	GO:0005737	cytoplasm	IDA	J:239205
Cellular Component	GO:0000791	euchromatin	IDA	J:235989
Cellular Component	GO:0016607	nuclear speck	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:239205
Cellular Component	GO:0005634	nucleus	IDA	J:175204
Cellular Component	GO:0005634	nucleus	IDA	J:175134
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:43752
Cellular Component	GO:0005634	nucleus	IDA	J:134978
Cellular Component	GO:0005634	nucleus	IDA	J:149456
Cellular Component	GO:0005667	transcription regulator complex	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0048675	axon extension	IGI	J:73779
Biological Process	GO:0007411	axon guidance	IMP	J:66507
Biological Process	GO:0007409	axonogenesis	IMP	J:80078
Biological Process	GO:0007409	axonogenesis	IMP	J:80078
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0071345	cellular response to cytokine stimulus	IDA	J:239205
Biological Process	GO:0071392	cellular response to estradiol stimulus	IDA	J:239215
Biological Process	GO:0032869	cellular response to insulin stimulus	IMP	J:235989
Biological Process	GO:0071453	cellular response to oxygen levels	ISO	J:155856
Biological Process	GO:1990791	dorsal root ganglion development	IMP	J:80078
Biological Process	GO:0007507	heart development	IGI	J:261834
Biological Process	GO:0030520	intracellular estrogen receptor signaling pathway	ISO	J:164563
Biological Process	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	IMP	J:239207
Biological Process	GO:0000165	MAPK cascade	ISO	J:164563
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:1904178	negative regulation of adipose tissue development	IMP	J:235989
Biological Process	GO:1902870	negative regulation of amacrine cell differentiation	IMP	J:182786
Biological Process	GO:0045596	negative regulation of cell differentiation	IMP	J:182786
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	IDA	J:30561
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:239217
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:175131
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:235989
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:239207
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:133489
Biological Process	GO:0050885	neuromuscular process controlling balance	IGI	J:73779
Biological Process	GO:0030182	neuron differentiation	IMP	J:107704
Biological Process	GO:0030182	neuron differentiation	IGI	J:134978
Biological Process	GO:0030182	neuron differentiation	IMP	J:33502
Biological Process	GO:0045773	positive regulation of axon extension	IMP	J:80078
Biological Process	GO:0010666	positive regulation of cardiac muscle cell apoptotic process	ISO	J:155856
Biological Process	GO:0045597	positive regulation of cell differentiation	IMP	J:182786
Biological Process	GO:0045597	positive regulation of cell differentiation	IMP	J:220735
Biological Process	GO:0045597	positive regulation of cell differentiation	IMP	J:133489
Biological Process	GO:0046326	positive regulation of glucose import	IMP	J:235989
Biological Process	GO:0045672	positive regulation of osteoclast differentiation	IMP	J:239205
Biological Process	GO:0043068	positive regulation of programmed cell death	IMP	J:239207
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:235989
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:235989
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:139182
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:41168
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:239195
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:239207
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:134978
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:134978
Biological Process	GO:2000679	positive regulation of transcription regulatory region DNA binding	IDA	J:239215
Biological Process	GO:0051090	regulation of DNA-binding transcription factor activity	IDA	J:239215
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0010468	regulation of gene expression	ISO	J:155856
Biological Process	GO:0090259	regulation of retinal ganglion cell axon guidance	IMP	J:66507
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0060041	retina development in camera-type eye	IMP	J:107704
Biological Process	GO:0060041	retina development in camera-type eye	IMP	J:33502
Biological Process	GO:0031290	retinal ganglion cell axon guidance	IMP	J:134978
Biological Process	GO:0031290	retinal ganglion cell axon guidance	IGI	J:73779
Biological Process	GO:0007605	sensory perception of sound	IGI	J:73779