Igk
Complex/Cluster/Region Detail

Symbol Name ID

Igk immunoglobulin kappa chain complex MGI:96494

Synonyms

kappa

Feature Type

complex/cluster/region

Genetic Map

Chromosome 6

30.89 cM, cytoband F1-pter
Detailed Genetic Map ± 1 cM


Mapping data(44)

Vertebrate homology

Protein SuperFamily: immunoglobulin V region

Alleles and phenotypes

All alleles(19) : Targeted(19)
 

Mice homozygous for a knock-out allele exhibit abnormal B cell number and differentiation.

 
Alleles Annotated to Human Diseases(1)   

Expression

External Resources: GEO  

Molecular reagents

All nucleic(11) Genomic(6) cDNA(2) Primer pair(1) Other(2)

Other database links

Entrez Gene

243469 (Evidence)

Sequences

Length	Strain/Species
transcript	AJ880391	GenBank | EMBL | DDBJ | MGI Sequence Detail	333	Not Specified
polypeptide	Q5F2I7	UniProt | EBI | MGI Sequence Detail	111	Not Applicable

All sequences(3) RefSeq(1) UniProt(1)

Polymorphisms

All PCR and RFLP(4) : PCR(1) RFLP(3) SNPs(0 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR007110	Immunoglobulin-like
InterPro	IPR013783	Immunoglobulin-like fold
InterPro	IPR013106	Immunoglobulin V-set
InterPro	IPR003596	Immunoglobulin V-set, subgroup

References

(Earliest) J:6050 Hengartner H, et al., Assignment of genes for immunoglobulin kappa and heavy chains to chromosomes 6 and 12 in mouse. Proc Natl Acad Sci U S A. 1978 Sep;75(9):4494-8
(Latest) J:193015 Xiang Y, et al., Vkappa Gene Repertoire and Locus Contraction Are Specified by Critical DNase I Hypersensitive Sites within the Vkappa-Jkappa Intervening Region. J Immunol. 2013 Feb 15;190(4):1819-26
All references(171)

Other accession IDs

MGD-MRK-11292