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Igk Complex/Cluster/Region Detail
Summary
  • Symbol
    Igk
  • Name
    immunoglobulin kappa chain complex
  • Synonyms
    kappa
  • Feature Type
    complex/cluster/region
  • IDs
    MGI:96494
    NCBI Gene: 243469
Location & Maps
more
  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 6, 30.89 cM, cytoband F1-pter
  • Mapping Data
    44 experiments
Homology
less
Human Diseases
less
  • Mutations/Alleles
    2 with disease annotations
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    30 phenotypes from 14 alleles in 12 genetic backgrounds
    55 phenotypes from multigenic genotypes
    131 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    45
  • Targeted
    25
  • Transgenic
    20
Mice homozygous for a knock-out allele exhibit abnormal B cell number and differentiation.
Expression
less
  • Other Mouse Links
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
transcript AJ880391 GenBank | EMBL | DDBJ | MGI Sequence Detail 333 Not Specified  
polypeptide Q5F2I7 UniProt | EBI | MGI Sequence Detail 111 Not Applicable  
For the selected sequence
Polymorphisms
less
  • PCR
  • RFLP
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    Genomic 6
    cDNA 2
    Primer pair 1
    Other 2
Other
Accession IDs
less
MGD-MRK-11292
References
more
  • Summaries
    All 191
    Diseases 2
    Phenotypes 131
  • Earliest
    J:6050 Hengartner H, et al., Assignment of genes for immunoglobulin kappa and heavy chains to chromosomes 6 and 12 in mouse. Proc Natl Acad Sci U S A. 1978 Sep;75(9):4494-8
  • Latest
    J:233381 Mandal M, et al., Histone reader BRWD1 targets and restricts recombination to the Igk locus. Nat Immunol. 2015 Oct;16(10):1094-103

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory