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Igk
Complex/Cluster/Region Detail
 Symbol
Name
ID
Igk
immunoglobulin kappa chain complex
MGI:96494
Synonyms kappa
Feature Type complex/cluster/region
Genetic Map
Chromosome 6
30.89 cM, cytoband F1-pter
Detailed Genetic Map ± 1 cM


Mapping data(44)
Vertebrate
homology
Protein SuperFamily: immunoglobulin V region
Mutations,
alleles, and
phenotypes
All mutations/alleles(21) : Targeted(21)
 
Mice homozygous for a knock-out allele exhibit abnormal B cell number and differentiation.
 
Alleles Annotated to Human Diseases(1)   
Expression
External Resources: GEO  
Molecular
reagents
All nucleic(11) Genomic(6) cDNA(2) Primer pair(1) Other(2)
Other database
links
Entrez Gene243469 (Evidence)
Sequences
Representative SequencesLengthStrain/SpeciesFlank
transcript AJ880391 GenBank | EMBL | DDBJ | MGI Sequence Detail 333 Not Specified 
polypeptide Q5F2I7 UniProt | EBI | MGI Sequence Detail 111 Not Applicable 

For the selected sequences
All sequences(3) RefSeq(1) UniProt(1)
Polymorphisms All PCR and RFLP(4) : PCR(1) RFLP(3) SNPs within 2kb(0 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR013106 Immunoglobulin V-set
InterPro IPR003596 Immunoglobulin V-set, subgroup
References (Earliest) J:6050 Hengartner H, et al., Assignment of genes for immunoglobulin kappa and heavy chains to chromosomes 6 and 12 in mouse. Proc Natl Acad Sci U S A. 1978 Sep;75(9):4494-8
(Latest) J:209415 Kirchenbaum GA, et al., Functionally responsive self-reactive B cells of low affinity express reduced levels of surface IgM. Eur J Immunol. 2014 Apr;44(4):970-82
All references(181)
Other
accession IDs
MGD-MRK-11292

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory