Iac
Gene Detail

Symbol Name ID

Iac iris anomaly with cataract MGI:96305

Feature Type

heritable phenotypic marker

Genetic Map

Chromosome Unknown

Alleles and phenotypes

All alleles(1) : Radiation induced(1)
 

Heterozygotes exhibit microphthalmia, abnormally shaped pupils with impaired pupillary reaction, cortical or total lens opacity, reduced survival, and occasionally long teeth. Homozygotes are inviable.

 
Human Diseases Modeled Using Mouse Iac (1)    Alleles Annotated to Human Diseases(1)   

Other database links

Entrez Gene

104377

References

(Earliest) J:6686 Kratochvilova J, Dominant cataract mutations detected in offspring of gamma-irradiated male mice. J Hered. 1981 Sep-Oct;72(5):302-7
(Latest) J:9528 Kratochvilova J, et al., Phenotypic characterization and genetic analysis of twenty dominant cataract mutations detected in offspring of irradiated male mice. Genet Res. 1988 Oct;52(2):125-34
All references(3)

Other accession IDs

MGD-MRK-11054