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Naipc Complex/Cluster/Region Detail
Summary
  • Symbol
    Naipc
  • Name
    NLR family, apoptosis inhibitory protein cluster
  • Feature Type
    complex/cluster/region
  • IDs
    MGI:5614493
  • Cluster Members
    Naip2, Naip1-rs1, Naip5 ... (11 members)
Location & Maps
less
  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 13, Syntenic
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 2 alleles in 3 genetic backgrounds
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit increased incidence of AOM- and DSS-induced tumors and decreased incidence of DSS-induced colitis.
References
more
  • Summaries
    All 2
    Phenotypes 1
  • Earliest
    J:222114 Allam R, et al., Epithelial NAIPs protect against colonic tumorigenesis. J Exp Med. 2015 Mar 9;212(3):369-83

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory