Tg(Igk)5Cys
Transgene Detail

Summary

• Symbol: Tg(Igk)5Cys
• Name: transgene insertion 5, Jason G Cyster
• MGI ID: MGI:3702699
• Synonyms: k5, k5 HyHel10, k5 HyHEL10 light chain transgenic
• Transgene: Tg(Igk)5Cys Location: unknown
• Alliance: Tg(Igk)5Cys page

Transgene origin

• Strain of Origin: (C57BL/6 x CBA)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Igk)5Cys expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Igk (MGI:96494)

• Mutation details: The transgenic construct contained the VJk exon of the HyHEL10 kappa light chain (Igk), the kappa-constant region, and 3' flanking DNA including the kappa enhancer elements. Founder line 5 carries 5-10 copies of the transgene. (J:118931)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:118931 Allen CD, et al., Imaging of germinal center selection events during affinity maturation. Science. 2007 Jan 26;315(5811):528-31
• All: 15 reference(s)