sar Gene Detail

Summary

• Symbol
  sar
• Name
  sarcosinemia autosomal recessive

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:107680
  NCBI Gene: 20223
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 2, Syntenic
• Mapping Data
  1 experiment

Human Diseases

• Diseases
  1 with sar mouse models

Human Disease

Mouse Models

sarcosinemia

IDs

sarcosinemia      

DOID:0112307
ICD10CM:E72.59
MESH:C537236
OMIM:268900
ORDO:3129
UMLS_CUI:C0268563

View 1 model

Mouse Models

Human Disease Modeled: sarcosinemia

Allelic Composition	Genetic Background	Reference	Phenotypes
sar/sar	BTBR-sar	J:37	View

Click on a disease name to see all genes associated with that disease.

• Mutations/Alleles
  1 with disease annotations

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  9 phenotypes from 1 allele in 1 genetic background
  2 phenotype references
  

• All Mutations and Alleles
  1
• Chemically induced (ENU)
  1
• Find Mice (IMSR)
  0 strains or lines available

Sequences &
Gene Models

• NCBI Gene
  20223

Other
Accession IDs

MGD-MRK-36255

References

• Summaries
  All 3

  Diseases 1

  Phenotypes 2
• Earliest
  J:37 Harding CO, et al., sar: a genetic mouse model for human sarcosinemia generated by ethylnitrosourea mutagenesis. Proc Natl Acad Sci U S A. 1992 Apr 1;89(7):2644-8
• Latest
  J:34880 Brunialti AL, et al., The mouse mutation sarcosinemia (sar) maps to chromosome 2 in a region homologous to human 9q33-q34. Genomics. 1996 Aug 15;36(1):182-4