Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  7
• Reference
  J:18520 Watanabe H, et al., Mouse cartilage matrix deficiency (cmd) caused by a 7 bp deletion in the aggrecan gene. Nat Genet. 1994 Jun;7(2):154-7
• ID
  MGI:43626

Genes

Gene	Assay Type	Description
Gpi1	reported elsewhere
Gabra4	reported elsewhere
Hras1-ps1	reported elsewhere
Acan	Southern analysis	Agc cDNA1
Tyr	reported elsewhere
Zp2	reported elsewhere

Notes

• Reference
  cmd (cartilage matrix deficiency) is a mutation at the Agc locus caused by a 7bp deletion in exon 5 of Agc. Authors report Gabra4 mapping to Chromosome 7, subsequent data report this locus mapping to Chromosome 5, see J:62530 (Tarantino LM, Genomics 2000;66:55-64)
• Experiment
  Offspring types indicate alleles inherited from F1 parent.
  F1 direction known.
  

CROSS

• Type
  Backcross, female
• Female Parent
  <n> <n> <n> <n> <n> <n>/<s> <s> <s> <s> <s> <s>
• Strain
  (NFS/N x M. spretus)F1
• Male Parent
  <s> <s> <s> <s> <s> <s>/<s> <s> <s> <s> <s> <s>
• Strain
  M. spretus or C58/J
• Allele 1
  n from NFS/N
• Allele 2
  s from M. spretus or C58/J

2x2 Data Reported

Marker 1	Marker 2	# Recombinants	# Parentals
Gpi1	Gabra4	15	87
Gabra4	Hras1-ps1	4	80
Hras1-ps1	Acan	4	83
Acan	Tyr	9	99
Tyr	Zp2	12	90

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Gabra4	Hras1-ps1	4	84	4.762	2.324
Gpi1	Gabra4	15	102	14.706	3.507
Hras1-ps1	Acan	4	87	4.598	2.245
Tyr	Zp2	12	102	11.765	3.190
Acan	Tyr	9	108	8.333	2.660