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Mapping Data
Experiment
  • Experiment
    TEXT
  • Chromosome
    17
  • Reference
    J:7337 Fox HS, et al., An alpha globin pseudogene is located within the mouse t complex. Immunogenetics. 1984;19(2):125-30
  • ID
    MGI:40206
Genes
GeneAlleleAssay TypeDescription
t
Tcp1
Itpr3
Hba-ps4
Notes
  • Experiment
    A genomic clone that identifies the hemoglobin alpha pseudogene, alpha 4 (Hba-ps4) was mapped to the distal t complex. TaqI digests produced a t specific Hba-ps4 fragment of 5.2 kb in complete T haplotypes from 129 mice, whereas wild type fragments of 3.8 and 1.4 kb in C3H mice and 3.4 kb in BALB/cJ mice were observed. All partial proximal t-haplotypes th17, th18, tTu2 and tLub2) were associated with the wild type inbred fragments whereas the 5.2 kb Hba-ps4 specific fragment was associated with proximal t haplotype th2, t3, tw18, tAE5, th45, th49, th51, th53, th44 and TOrl ) which are bounded proximally by Tcp-1. Further it was noted that a deletion in a segment of the t Chromosome in t6 including Hba-ps4 deriving the th20haplotype coincided with the appearance of the Itpr3tf mutation in th20, demonstrating the two may be linked.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/22/2022
MGI 6.21
The Jackson Laboratory