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Mapping Data
Experiment
  • Experiment
    TEXT-QTL
  • Chromosome
    9
  • Reference
    J:50271 Risinger FO, et al., Ethanol-induced conditioned taste aversion in BXD recombinant inbred mice. Alcohol Clin Exp Res. 1998 Sep;22(6):1234-44
  • ID
    MGI:2157424
Genes
GeneAlleleAssay TypeDescription
Etohcta8 visible phenotype
D9Mit10
Htr1b reported elsewhere
Notes
  • Experiment
    841 male mice 56-125 days of ages from 20 BXD/Ty RI strains were used to map QTLs associated with ethanol-induced conditioned taste aversion behavior. Inbred strain DBA/2J exhibits increased sensitivity to ethanol compared to C57BL/6J and decreases consumption of an ethanol-paired distinctive taste (ethanol-induced taste aversion) in a dose dependent manner. Saccharin solution drinking water was used as the paired taste in this study. Etohcta8 (P<0.01 at D9Mit10) mapped to Chromosome 9 at 49 cM. Etohcta8 is associated with ethanol-induced taste aversion at low-dose ethanol injection following the paired taste. A potential candidate gene mapping near Etohcta8 is the serotonin receptor, Htr1b.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/30/2021
MGI 6.16
The Jackson Laboratory