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Mapping Data
Experiment
  • Experiment
    TEXT
  • Chromosome
    6
  • Reference
    J:32389 Hochtl J, et al., A novel type of aberrant recombination in immunoglobulin genes and its implications for V-J joining mechanism. Nature. 1983 Mar 17-23;302(5905):260-3
  • ID
    MGI:1331711
Genes
GeneAlleleAssay TypeDescription
D6Hgz1 direct sequencing L10 clones, K-41 clones,f-41
Igkj1 direct sequencing L10 clones, K-41 clones,f-41
Igkj2 reported elsewhere
Igkj3 reported elsewhere
Igkj4 reported elsewhere
Igkj5 reported elsewhere
Igkc direct sequencing L10 clones, K-41 clones
Notes
  • Experiment
    The authors observed that both D6Hgz1 (authors calls it L10) and Igk-C sequences are deleted in tumor RPC20, suggesting that there is physial linkage between the two DNA segments. Clones derived from MOPC41 myeloma cells indicate that abberant reciprocalrecombination of the D6Hgz1 and Igk-J1 genes occurs. This recombination merges the 5' -flank of Igk-J1 and the 3' -flank D6Hgz1 (fragment f-41) and the 3' -flank of Igk-J1 with the 5' -flank of D6Hgz1 (fragment K-41). Non-recombinant gene order on mouse Chromosome 6 is reported as: 3' - D6Hgz1 - 5' - Igk-J1 - Igk-J2 - Igk-J3 - Igk-J4 - Igk-J5 - Igk-C.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory