HXB-1-43.

Inbr.F17-21 (Ipcv 1988).

Origin: Set of 17 recombinant inbred strains developed by Pravenec, Klir and Kren from a cross between SHR/OlaIpcv and BN.ix/CubIpcv, and described by Pravenec et al (1988). Strains have now been typed at 500 loci and scanned for quantitative trait loci associated with blood pressure and heart weight (Pravenec et al, 1995).

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Pravenec M., Klir P., and Kren V. (1988) The assignment of ES-6 locus to the LGVII of the rat and the production of HXB set of recombinant inbred strains. Rat News Lett. 20, 12-13.

Pravenec M., Gauguier D., Schott J. J., Buard J., Kren V., Bila V., Szpirer C., Szpirer J., Wang J. M., Huang H. M., Stlezin E., Spence M. A., Flodman P., Printz M., Lathrop G. M., Vergnaud G., and Kurtz T. W. (1995) Mapping of quantitative trait loci for blood-pressure and cardiac mass in the rat by genome scanning of recombinant inbred strains. J. Clin. Invest. 96, 1973-1978.

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INBRED STRAINS OF RATS
Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK