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Inbred Strains of Mice: XVII

XVII

Inbr: F80 (Rd). Albino. Genet: c. Origin: Dobrovolskaia-Zavadskaia 1928; b x s inbreeding since 1943.


Characteristics

No mammary tumours or leukaemia; pulmonary adenomas 19.5% after 13 months; mammary tumours 1.3%, leukaemia females 0.4%, males 1.6%; lung tumour females 5.1%, males 8.8%; sensitive to Graffi leukaemia agent (Krischke and Graffi, 1962); blood catalase has low specific activity (7/7) (Magdon, 1962); strong reactivity against specific antigens of carcinogen-induced sarcomas (Pasternak, 1963); very susceptible to lung oncogenesis by chemical agents.


Krischke W. V. and Graffi A. (1962) Weitere versuch zur abhangigkeit der Wirkung des virus der myeloischen leukamie der Maus von versuchiedenen biologischen Bedingangen der infizierten tiere. Arch. Geschwulstforsch. 20, 22-29. \par

Magdon E. von (1962) Untersuchungen der katalaseaktivitat des Blutes vershiedener Mausestamme. Z. Versuchstierk. 1, 173-178. \par

Pasternak G. (1963) Die unterschiedliche Reaktionsfähigkeit zweier Mausein-zuchtstamme gegen spezifische Antigens isolog transplantabler Carcinogentu-moren. Acta Biol. Med. Germ. 10, 572-578. \par


INBRED STRAINS OF MICE
Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK

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last database update
06/20/2017
MGI 6.10
The Jackson Laboratory