of Mice: SEN
Inbr (Or) 20. Albino c.
Origin: From outbred "SENCAR" mice produced
by Boutwell (1964
) using Rockland-derived
mice from A.Sutter, Springfield Mo. Selected for skin tumors following
initiation by DMBA and promotion with croton oil. Later crossed with outbred
CD-1 mice. To McArdale Lab. for Cancer Research, to Oak Ridge. Inbred
by Sloga in 1979 with further selection to F9 for skin tumors following
treatment with DMBA and TPA. Maint. by Or.
Boutwell R. K.
(1964) Some biological aspects of skin carcinogenesis. Prog. Exp.
Tumor Res. 4, 207-250.
INBRED STRAINS OF MICE
Updated 9 Apr. 1998
MRC Toxicology Unit, Hodgkin Building,
University of Leicester,