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Inbred Strains of Mice: SEN


Inbr (Or) 20. Albino c. Origin: From outbred "SENCAR" mice produced by Boutwell (1964) using Rockland-derived mice from A.Sutter, Springfield Mo. Selected for skin tumors following initiation by DMBA and promotion with croton oil. Later crossed with outbred CD-1 mice. To McArdale Lab. for Cancer Research, to Oak Ridge. Inbred by Sloga in 1979 with further selection to F9 for skin tumors following treatment with DMBA and TPA. Maint. by Or.

Boutwell R. K. (1964) Some biological aspects of skin carcinogenesis. Prog. Exp. Tumor Res. 4, 207-250. \par

Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK

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