of Mice: SEC
Pale brown: a,b,cch.
prior to 1946 from a cross between NB and BALB/c. Carries se
gene causing short ears and skeletal abnormalities. Substrains as follows:
Inbr (Rl) 100 +. Colour ?: a,b,cch,d,se
.Origin: E.L.Green 1948 to Rl at F20-F21. Maint. by J.
Inbr (Le) 149. Gets multiple lung cysts, especially in se/se
Inbr (J) 138. From SEC/1Gn, but short-ear eliminated by E.S.Russell.
High shuttle-box avoidance (2/5) (Messeri
et al., 1972
., 1972). High plasma cholinesterase activity (7/22 in
females, 2/22 in males) (Angel et al., 1967
1967). High hepatic delta-aminolaevulinic acid synthetase activity after
DDC treatment (3/15) (Gross and Hutton, 1971
Low sensitivity of females to X-irradiation (5/5) (Ehling,
). Low lymphocyte phytohaemagglutinin response (31/43) (Heiniger et al., 1975
., 1975). Good reproductive performance
(1/5) (Ehling, 1964
R., Mahin D. T., Farris R. D., and Woodward K. T. (1967) Heritability
of plasma cholinesterase activity in inbred mouse strains. Science
Ehling U. H. (1964)
Strain variation in reproductive capacity and radiation response of female
mice. Radiation Res. 23, 603-610.
and Hutton J. (1971) Induction of hepatic -aminolaevulinic acid synthetase
activity in strains of inbred mice. J. Biol. Chem. 246,
H. J., Taylor B. A., Hards E. J., and Meier H. (1975) Heritability of
the phytohaemagglutinin responsiveness of lymphocytes and its relationship
to leukemogenesis. Cancer Res. 35, 825-831.
P., Oliverio A., and Bovet D. (1972) Relations between avoidance and activity.
A diallel study in mice. Behav. Biol. 7, 733-742.
INBRED STRAINS OF MICE
Updated 9 Apr. 1998
MRC Toxicology Unit, Hodgkin Building,
University of Leicester,