of Mice: PBA
Inbr: F20 +. Albino. Genet: c. Origin: P. C. Bailey from a pair of pet
shop mice purchased in Birmingham, Alabama, in 1958.
Litter size 6.1; 6 week weight 21 g (both sexes); mean life-span 317 days
in males, 268 days in females. Spontaneous lymphomas 100%, mammary tumours
74%, pulmonary adenomas 77% in animals over 1 year (Bailey et al., 1970
., 1970). Development of spontaneous adenomas
associated with increased serum concentration of IgG1
immunoglobulins (Schrohenloher and
P. C., Leach W. B., and Hartley M. W. (1970) Characteristics of a new
inbred strain of mice (PBA) with a high tumor incidence: preliminary report.
J. Natl. Cancer Inst. 45, 59-73.
Schrohenloher R. E. and Bailey P. C. (1972) Atypical immunoglobulins
associated with spontaneous lymphomas in an inbred strain of mice. J.
Natl. Cancer Inst. 49, 1027-1037.
INBRED STRAINS OF MICE
Updated 9 Apr. 1998
MRC Toxicology Unit, Hodgkin Building,
University of Leicester,